Skip to main content

Cyclobenzaprine for Fibromyalgia User Reviews (Page 2)

Brand names: Amrix Comfort Pac with Cyclobenzaprine

Cyclobenzaprine has an average rating of 7.7 out of 10 from a total of 51 reviews for the off-label treatment of Fibromyalgia. 78% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Cyclobenzaprine

  • Cathy...
  • April 21, 2012

Amrix (cyclobenzaprine) "I was diagnosed with Fibromyalgia over a year ago, after many years of chronic pain, insomnia and fatigue. Sleep study showed no stage 3 or 4 sleep so the sleep I was getting was not good sleep. I am on several medications now to stay awake during the day, control my pain so I can continue to work and more medications to sleep. Restoril has helped in all three areas."

9 / 10
Was this helpful?YesNo
32 Report
  • Anonymous
  • February 15, 2011

Amrix (cyclobenzaprine) "This medicine has helped greatly reduce pain, and has made it possible for me to take less pain medication. The only problem I have had with it is if I take it too late in the evening, it is sometimes very hard to wake up the next morning. It is best for me, at least, to take it at least 10 hours before I need to wake up."

9 / 10
Was this helpful?YesNo
30 Report
  • Anonymous
  • May 6, 2011

Amrix (cyclobenzaprine) "When I first had pain 19 years ago, I was treated with Flexeril for six months. I thought I was getting better. I stopped taking Flexeril and it was a false feeling of wellness. Two months later I was diagnosed with Fibromyalgia. Now I am on Flexeril again after a car accident and it is helping. I only plan to stay on it a few weeks since I fear addiction."

9 / 10
Was this helpful?YesNo
24 Report

Frequently asked questions

  • rac
  • Taken for less than 1 month
  • March 28, 2019

"Took this for less than a week my blood pressure was high and my heart beat was high. I could hear my heart beating through my ear made me nervous and I felt a lot if anxiety. It took me a few days to feel normal once I stopped it"

1 / 10
Was this helpful?YesNo
12 Report
  • Random...
  • Taken for 1 to 6 months
  • December 15, 2019

"I take cyclobenzaprine occasionally for fibromyalgia pain and overuse of muscles from crocheting. I can't tolerate more than 7.5mg per night because it will cause leg cramps. It's a good sleep and relaxation aid. If it didn't dry my mouth out so terribly I'd give it a 10."

8 / 10
Was this helpful?YesNo
10 Report

Are you taking this medicine?

  • Kquix...
  • Taken for 1 to 6 months
  • September 1, 2018

"I have Fibromyalgia as well as sciatica and it has helped with both pain and sleep. Every evening between 7 pm and 8pm I take 10mg which helps me sleep through the night and have less pain the next day."

8 / 10
Was this helpful?YesNo
12 Report
  • Akchick
  • Taken for 6 months to 1 year
  • May 15, 2018

"After years of muscle tightness spasms and horrific pain I was finally diagnosed with fibro. The condition of muscle tightness had me on flexaril first. The condition always returns after meds ran out. With FM diagnosis came Cymbalta. Which helped some. The magic was lyrica and flexaril. I can function semi normal if I don't over do things I can stay pain free (although the pain is still there a missed dose of all my meds showed me this). Flexaril has helped me so much and I am ever so grateful for the semi normal life. Medicines wear off on me and stop working after a while so I pretty much have to switch every few months. Honestly I don't mind switching every few months. I did at first."

9 / 10
Was this helpful?YesNo
12 Report

More FAQ

  • Anonymous
  • March 19, 2011

Amrix (cyclobenzaprine) "I used Amirix with Klonopin and Pristiq and I sleep, finally. The combination works for me. The only problem it takes me a while to open my eyes in the morning. I am disabled so this side effect is not a problem."

9 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • September 20, 2009

Amrix (cyclobenzaprine) "This medicine has been amazing for me. I was unable to sleep on my right side for the last 5 years due to pain, and now I can, with almost no pain. The only down sides are that it causes extreme "dry mouth" for me (which gets worse when I am nervous) and constipated. But it is worth it for the pain relief I am getting."

8 / 10
Was this helpful?YesNo
22 Report
  • Anonymous
  • May 25, 2010

Amrix (cyclobenzaprine) "I used Savella for three years without any significant relief other than helping me cope with the ongoing pain. Tried Lyrica which seemed to cause anxiety but recently my pain management doctor started me on Amrix which I take at dinner time and Gabapentin (Neurontin) which I take at bedtime with Ambien. This combination seems to be amazing. I hope it is not short lived."

Was this helpful?YesNo
20 Report
  • dayday
  • December 6, 2009

"I was diagnosed with Fibromyalgia a few years back, and there was no way to help control my pain and stiffness except narcotic pain pills. About a year ago, I started trying to take Flexeril during the day to help with the tight feeling tenderness. It made me too drowsy to use during the day. So then I started to take 10mg at night and it helped some with the muscle tenderness. I then tried taking 20mg at night and it really helps with the next day tenderness. I take it in conjunction with Lyrica and it works well to ease most of the Fibromyalgia pain. The only problem is that it leaves me with a dry mouth in the morning. The drowsiness isn't a problem as long as it's taken at night. It relaxes the all muscles, and that helps the Fibromyalgia pain."

9 / 10
Was this helpful?YesNo
20 Report
  • Kat
  • Taken for 1 to 2 years
  • September 26, 2020

"The secret to Cyclobenzaprine working is multiple, rapid dosing. The magic lies in the long, strong half life. I typically start with 20mgs and 30-45 minutes later take another 10mgs. And possibly another 10mgs within an hour after that. I've never needed more than that in a session, or couldn't stay awake to take more anyhow. In only the most severe instance did I do another session about 16 hours later, and it was the initial 20mgs followed by another 10mgs. I find it pairs with ibuprofen or naproxen effectively. I notice a good mood for a few days after using and have experimented with 10mgs as a nightly routine against depression with outstanding results. It can bring down bad trips, and using the pain session dosing works a million times better for my anxiety if I feel an attack coming on, like before dental work appointments, than Valium ever did."

9 / 10
Was this helpful?YesNo
7 Report
  • Maura...
  • Taken for 10 years or more
  • August 15, 2016

"I have been on this medication for about 10 years, since first getting diagnosed. Initially, they wanted me to take three times/day-I was a zombie. So, the rest of the time, I just have taken to sleep. Not really effective anymore for that."

2 / 10
Was this helpful?YesNo
12 Report
  • Anonymous
  • December 10, 2009

"I have used Flexeril for about 9 years now. It works great to ease my muscle pain and spasms. A lot of people have trouble with it making them sleepy but I have never had that trouble. I can take during the day with no drowsiness at all which is really nice. However it would be nice if it made me a little sleepy on the nights I am having trouble. It is a great medication and I am very grateful for it."

9 / 10
Was this helpful?YesNo
19 Report
  • SMM
  • Taken for 1 to 2 years
  • May 10, 2022

"Been taking Flexeril for a little over a year now for fibromyalgia, but only at bedtime. I sleep VERY sound, and don't really want to get up in the morning, which is a problem, since I have a full-time job! Recently, my husband asked his doctor if he would put him on a smaller dose of Flexeril, and his doctor said he wouldn't, because it's not meant for long-term use. So, I dug around and found this website, and SO glad I did! I have been feeling increasingly depressed, short-tempered, easily agitated, etc. and now I am wondering if it's the Flexeril! Thinking about taking melatonin instead, as I can't deal with being "Debby Downer" all the time...."

9 / 10
Was this helpful?YesNo
3 Report
  • MissL...
  • Taken for 1 to 6 months
  • July 13, 2018

"New primary doctor was concerned about my muscle pain and preliminarily diagnosed me with fibromyalgia and referred me to a rheumatologist. She also gave me Flexeril to see if it would help as it has been helpful for others. However, it was not for me. I noticed that I was very drowsy all the time and it interacted with my other meds. The major downside was it did nothing to relieve the pain from fibromyalgia, either, which was confirmed by a diagnosis from the rheumatologist."

1 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • August 6, 2012

Flexeril (cyclobenzaprine) "Felt very rested for once and pain went away."

9 / 10
Was this helpful?YesNo
74 Report
  • Anonymous
  • January 14, 2012

Flexeril (cyclobenzaprine) "Helps with the stiffness, didn't make me tired like some people have reported. Overall it has helped and I have had no negative side effects."

8 / 10
Was this helpful?YesNo
61 Report
  • Lifes...
  • October 6, 2012

Amrix (cyclobenzaprine) "Amrix is good for muscle cramps. It reduces pain from a 10 to a 7 for me. That is a big deal for me. I am 24/7 in pain. No medicine can reduce that pain below a 5."

8 / 10
Was this helpful?YesNo
49 Report
  • travl...
  • March 28, 2011

Flexeril (cyclobenzaprine) "Without this medicine I could not sleep through the pain."

8 / 10
Was this helpful?YesNo
44 Report
  • Jen
  • Taken for 1 to 6 months
  • September 21, 2018

"Been a total game changer. I take it at night and I actually sleep through the night again after 20 years of getting up 3 and 4 times from pain or mind not calming down and anxiety. Awesome."

10 / 10
Was this helpful?YesNo
19 Report
  • Anonymous
  • July 15, 2009

Flexeril (cyclobenzaprine) "Doesn't touch my pain while I am awake but puts me to sleep and in the morning I notice it helped relax bad spasms."

2 / 10
Was this helpful?YesNo
37 Report
  • The...
  • November 2, 2013

"I can't stay awake, and I'm still in pain. I'm very sensitive to all drugs tho. I was taking the 5mg."

2 / 10
Was this helpful?YesNo
23 Report
  • cuso
  • May 9, 2016

"Very good"

10 / 10
Was this helpful?YesNo
15 Report
  • allys...
  • September 1, 2016

"improved my daily quality of function with in the perception of working collaboratively,with other meds"

9 / 10
Was this helpful?YesNo
14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Fibromyalgia

Care guides

Symptoms and treatments

Medicine.com guides (external)