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Azithromycin for Sinusitis User Reviews (Page 5)

Brand names: Zithromax, Azithromycin Dose Pack, Z-Pak

Azithromycin has an average rating of 6.7 out of 10 from a total of 139 reviews for the treatment of Sinusitis. 56% of reviewers reported a positive experience, while 24% reported a negative experience.

Reviews for Azithromycin

  • Ijeland
  • Taken for less than 1 month
  • April 28, 2021

"I went to the Dr last Tuesday and was given a sinus cocktail injection for my stuffy nose, sneezing , running nose and etc. I haven’t had the cocktail in years but it did nothing for me shocking . My dr then prescribed me Azithromycin 250 mg tablets & I honestly feel worse than I did before I started the medicine. I am two days off the medicine and my nose is stuffy again . I am mad that I took this medicine. This my second time taking this medication and it did nothing this time ."

2 / 10
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1 Report
  • PJano
  • December 31, 2020

"I have used the Z pack on and off for years. This time they gave me the generic brand! It always had minimal side effects with the non-generic but with the generic, it was horrible. Stomach pains, nausea but the worst was diarrhea. I would NEVER take this generic brand again."

3 / 10
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1 Report
  • Sick...
  • Taken for less than 1 month
  • November 1, 2017

"Took first two pills for sinus and ear infection that I’ve had for months. Tried holistic stuff, but Only temp relief. I used to use this all the time and never once had reactions. Most generics usually turn to rubbish, this did too. Had instantaneous stomach bloating and indigestion (took with GF cereal) skin red and itchy, and worst of all I’ve suddenly got flu like symptoms. Feel like trash. 99.4 temp but feel like I’m on fire. Just a little advice here at the end for sufferers of chronic sinus infections and the like. Just found out why I’m sick all the time. IGG SUBCLASS DEFICIENCIES. I’m prone to get sinus infections and others. Have Rhumatologist or immunologist check your immune system. Finally found out why I’m so sickly."

3 / 10
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1 Report

Frequently asked questions

  • Anony...
  • Taken for less than 1 month
  • April 22, 2023

"My husband took this for a sinus infection. By day 4 he was experiencing severe anxiety, nightmares and difficulty sleeping due to those issues. He started having panic attacks and was restless. This drug is toxic. Stick to something safer like amoxicillin."

1 / 10
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  • Nonee...
  • Taken for less than 1 month
  • March 12, 2022

"First time I've been prescribed azithromycin for my sinus infection and it completely sucks for it compared to my typical amoxicillin. Three days in on the zpak and nothing, still have a fever, no change in sinus pressure and now a splitting headache with large amount of gas. At least with amoxicillin by the third day I would feel better, this nothing. I'll continue treatment just to see but highly doubt it."

1 / 10
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  • Gabby
  • Taken for less than 1 month
  • November 6, 2021

"I had a pretty severe sinus infection and was prescribed this to help with my symptoms. It definitely did it’s job, but oh my GOD. The worst stomach pain I’ve ever had in my life. I NEVER get side effects from medicine and I have had to take quite a good amount, but wow this was bad. I have no idea why I reacted with this antibiotic, but it was so bad that it would last the entire day any time I ate and I was afraid to eat on it. And I never have stomach issues so this was very hard for me. It does what it needs to, but I won’t lie it was some of the worst pain I’ve ever dealt with."

6 / 10
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  • judy...
  • Taken for less than 1 month
  • September 29, 2021

"Was prescribed it without a nasal lavage do not think I even have a sinus infection but chronic perennial allergic rhinitis and too many surgeries. Nothing after a 3 day and then one a week regime. The only side effect insomnia but it was bad"

3 / 10
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More FAQ

  • Best...
  • Taken for less than 1 month
  • April 7, 2024

"Azithromycin is the only antibiotic that works. Having been prescribed clarithromycin and doxycycline to no avail, this was prescribed as I had gotten worse and got an ear infection also, so was so unwell. High temperature and feeling dreadful. I've found Azithromycin to be fantastic."

10 / 10
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  • jenbro
  • February 6, 2014

Zithromax (azithromycin) "Many many sinus infections over the years. This knocks it out in 3 days compared to 10."

10 / 10
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104 Report
  • Pashon
  • December 26, 2015

Zithromax (azithromycin) "After trying other antibiotics. This was the only one that worked. The Doctor tried to tell me it would not work for Sinusitis. It is the only antibiotic that takes it away for me."

10 / 10
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59 Report
  • andre...
  • March 5, 2013

Zithromax (azithromycin) "I am one of the few that have not had a good experience. High anxiety because my heart won't slow down, bad headache, little nausea, and loose stool. I'm going tomorrow to get different antibiotics."

2 / 10
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53 Report
  • rags
  • November 13, 2008

Zithromax (azithromycin) "The only antibiotic that ALWAYS works on my recurring sinus infections. Easy on the stomach also."

10 / 10
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61 Report
  • yannick
  • December 9, 2013

Azithromycin Dose Pack (azithromycin) "Could be effective, not sure. Side effects from three day Pak; headache,nausea, anxiety, sore throat, chills, tired, a feeling of being very unwell."

7 / 10
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41 Report
  • Anonymous
  • September 18, 2008

Zithromax (azithromycin) "After I take the first dose (2 pills) within 8 to 10 hours I feel 50% better. It usually does not take more then 4 days to be well. This is a great medication for sinusitis."

10 / 10
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55 Report
  • Anonymous
  • February 2, 2016

Azithromycin Dose Pack (azithromycin) "It worked however on the fifth day of taking it i had an Supraventricular tachycardia (SVT). Later found out there was a study out that confirmed hearth Rythym issues."

7 / 10
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28 Report
  • ano
  • January 10, 2010

Zithromax (azithromycin) "I used this for every infection, now the sad part is I am resistant. I used the whole 5 day dose, felt a lot better, then the infection came back a week later."

8 / 10
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41 Report
  • Anonymous
  • January 17, 2012

"I'm on Day 4. My sinus infection is much better, but the diarrhea and upset stomach are bad. "

8 / 10
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35 Report
  • meiy...
  • Taken for less than 1 month
  • July 30, 2012

"It is useful but I have headaches during usage."

6 / 10
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32 Report
  • Anonymous
  • November 25, 2009

Azithromycin Dose Pack (azithromycin) "I have taken this many times and it clears up the problem with no side effects at all ."

10 / 10
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37 Report
  • Wili
  • Taken for less than 1 month
  • October 10, 2019

"I've done taking the med and I don't feel any improvement. I still have a sinus congestion headache and pressure in the ears. So I have to go see a doctor again ."

1 / 10
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13 Report
  • dandee
  • April 4, 2008

"I was givin this med for sinusitis and it did improve that but it caused stomache upset and diarrhea. I would prefer to be treated with something else from now on."

5 / 10
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32 Report
  • Mandas
  • September 26, 2011

"Although it is doing great for what it was prescribed for, I have awful side effects. I have been throwing up and been just very very nauseous all day."

3 / 10
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24 Report
  • Anonymous
  • June 10, 2008

Zithromax (azithromycin) "Worked well."

10 / 10
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28 Report
  • Andi
  • Taken for less than 1 month
  • March 8, 2018

Azithromycin Dose Pack (azithromycin) "Doc put me on a 5 day dosage to treat sinus infection, didn't miss a day, finished the dosage, and I still have a sinus infection."

1 / 10
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14 Report
  • Rick...
  • October 17, 2015

"I suffer from chronic sinusitis. allergic to doxycycline. azithromycin is a life saver. its great."

10 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Sinusitis

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Symptoms and treatments

Medicine.com guides (external)