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Azithromycin Pregnancy and Breastfeeding Warnings

Azithromycin is also known as: Azithromycin Dose Pack, Z-Pak, Zithromax, Zmax

Azithromycin Pregnancy Warnings

In one study comparing azithromycin and erythromycin, 15 pregnant women received one gram of azithromycin for the treatment of chlamydial infection. The period of gestation during which the drugs were given was not specified. Azithromycin was better tolerated than erythromycin, and no adverse fetal outcomes were reported.

Azithromycin has been assigned to pregnancy category B by the FDA. Animal studies failed to reveal evidence of fetotoxicity. There are no controlled data in human pregnancy. Azithromycin should only be given during pregnancy when benefit outweighs risk.

Azithromycin Breastfeeding Warnings

Azithromycin is excreted into human milk. The manufacturer recommends that caution be used when administering azithromycin to nursing women.

In one lactating woman receiving azithromycin 500 mg/day, azithromycin milk concentration measured 1.3 and 2.8 mcg/mL 1 hour after the first dose and 30 hours after the third dose, respectively.

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