Macrolides
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Macrolides are a class of antibiotics found in streptomycetes. They are natural lactones with a large ring, consisting of 14 to 20 atoms. Macrolides bind to the 50S subunit of the bacterial ribosome and inhibit ribosomal translocation, leading to inhibition of bacterial protein synthesis. Their action is primarily bacteriostatic but may be bactericidal at high concentrations, or depending on the type of microorganism.
Macrolides mainly affect gram-positive cocci and intracellular pathogens such as mycoplasma, chlamydia, legionella.
See also
Medical conditions associated with macrolides:
- Babesiosis
- Bacterial Endocarditis Prevention
- Bacterial Infection
- Bartonellosis
- Bowel Preparation
- Bronchitis
- Bullous Pemphigoid
- Campylobacter Gastroenteritis
- Cervicitis
- Chancroid
- Chlamydia Infection
- Clostridial Infection
- COPD, Acute
- Cystic Fibrosis
- Dental Abscess
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Helicobacter Pylori Infection
- Legionella Pneumonia
- Lyme Disease
- Lyme Disease, Erythema Chronicum Migrans
- Lymphogranuloma Venereum
- Mycobacterium avium-intracellulare, Prophylaxis
- Mycobacterium avium-intracellulare, Treatment
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Otitis Media
- Pelvic Inflammatory Disease
- Pemphigoid
- Pertussis
- Pharyngitis
- Pneumonia
- Rheumatic Fever Prophylaxis
- Sinusitis
- Skin and Structure Infection
- Skin Infection
- Strep Throat
- Streptococcal Infection
- Syphilis, Early
- Tonsillitis/Pharyngitis
- Toxoplasmosis
- Typhoid Fever
- Upper Respiratory Tract Infection
