Generic Name: cimetidine (sye-MET-i-deen)
Brand Name: Tagamet

Tagamet is used for:

Treating and preventing ulcers of the stomach and small intestine, and treating gastroesophageal reflux disease (GERD). It may be used for treating esophagitis (inflammation of the esophagus) caused by acid reflux and certain conditions that cause increased acid secretion (eg, Zollinger-Ellison syndrome). It may also be used to treat other conditions as determined by your doctor.

Tagamet is an H2(histamine) blocker. It works by blocking one of the chemicals, histamine, that stimulates the release of acid into the stomach. This reduces acidity in the stomach.

Do NOT use Tagamet if:

  • you are allergic to any ingredient in Tagamet
  • you are taking medicine for cancer (nitrosoureas)
  • you are taking cisapride, dofetilide, or a nitrosoureas (eg, carmustine)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Is it Safe to Give Human Medicine to Pets?

Always get your pet's drug and dose recommendation from the veterinarian.

Before using Tagamet:

Some medical conditions may interact with Tagamet. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems

Some MEDICINES MAY INTERACT with Tagamet. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Many prescription medicines (eg, those used for angina, asthma, arrhythmias, blood thinning, cancer, erectile dysfunction, high blood pressure, infections, pain, psychiatric disorders, seizures, other conditions) may interact with Tagamet, increasing the risk of side effects, some potentially life-threatening.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tagamet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tagamet:

Use Tagamet as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Tagamet by mouth with or without food.
  • Do not take an antacid within 1 hour before or after you take Tagamet.
  • If you also take cephalosporin (eg, cephalexin), itraconazole, or ketoconazole, take it at least 2 hours before taking Tagamet. Check with your doctor if you have questions.
  • If you miss a dose of Tagamet and you are taking it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tagamet.

Important safety information:

  • Tagamet may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Tagamet with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • It may be necessary to make significant lifestyle changes to assist in the treatment and prevention of ulcers and other digestive problems that include stress-reduction programs, exercise, and dietary changes.
  • If your symptoms do not get better within a few days, or if they get worse, check with your doctor.
  • Never self-diagnose or self-treat ulcers with this or any other medicine.
  • Notify your doctor if you experience black, tarry stools or vomit that looks like coffee grounds.
  • Do not drink alcohol while you are using Tagamet.
  • Do not smoke or use other tobacco products while using Tagamet.
  • Additional monitoring of your dose or condition may be necessary if you are also taking zaleplon.
  • Use Tagamet with caution in the ELDERLY; they may be more sensitive to its effects.
  • Tagamet should be used with extreme caution in CHILDREN younger than 16 years old; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tagamet while you are pregnant. Tagamet is found in breast milk. Do not breast-feed while taking Tagamet.

Possible side effects of Tagamet:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; anxiety; breast enlargement; breast lumps; confusion; depression; disorientation; fatigue; hallucinations; hair loss; joint or muscle pain; pain, redness or swelling at injections site; skin flushing or redness; sexual difficulties; slow or fast heartbeat.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; fast heartbeat; restlessness; tremors; vomiting.

Proper storage of Tagamet:

Store Tagamet at room temperature between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tagamet out of the reach of children and away from pets.

General information:

  • If you have any questions about Tagamet, please talk with your doctor, pharmacist, or other health care provider.
  • Tagamet is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Tagamet or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Tagamet. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Tagamet. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Tagamet.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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