Flexeril

Pronunciation

Generic Name: cyclobenzaprine (SYE-kloe-BEN-za-preen)
Brand Name: Flexeril

Flexeril is used for:

Treating muscle spasms caused by painful muscle conditions. It should be used along with rest and physical therapy. It may also be used for other conditions as determined by your doctor.

Flexeril is a muscle relaxant. It works in parts of the brain and nervous system to help reduce muscle spasms.

Do NOT use Flexeril if:

  • you are allergic to any ingredient in Flexeril
  • you have an overactive thyroid, moderate to severe liver problems, or certain heart problems (eg, irregular heartbeat, congestive heart failure, heart block, conduction problems), or if you have recently had a heart attack
  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine, rasagiline) in the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: 10 Common Sleep Disorders: Treatments and Truths

Before using Flexeril:

Some medical conditions may interact with Flexeril. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver problems, heart problems, cerebral palsy, brain or spinal cord disease, or stroke
  • if you have a history of glaucoma, increased pressure in the eye, or trouble urinating

Some MEDICINES MAY INTERACT with Flexeril. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Bupropion, MAOIs (eg, phenelzine, rasagiline), meperidine, serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, venlafaxine), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), tramadol, tricyclic antidepressants (eg, amitriptyline), or verapamil because the risk of certain severe side effects called serotonin syndrome may be increased
  • Anticholinergics (eg, methscopolamine, benztropine), barbiturates (eg, phenobarbital), cimetidine, fluconazole, fluvoxamine, mibefradil, or phenothiazines (eg, chlorpromazine) because they may increase the risk of Flexeril's side effects
  • Guanethidine or guanfacine because their effectiveness may be decreased by Flexeril

This may not be a complete list of all interactions that may occur. Ask your health care provider if Flexeril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Flexeril:

Use Flexeril as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Flexeril by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Do not suddenly stop taking Flexeril without checking with your doctor.
  • If you miss a dose of Flexeril, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Flexeril.

Important safety information:

  • Flexeril may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Flexeril with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Talk with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are take Flexeril; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do NOT take more than the recommended dose or use for longer than 2 to 3 weeks without checking with your doctor.
  • If your symptoms (eg, pain, tenderness, decreased range of motion) do not get better within 2 to 3 weeks or if they get worse, contact your doctor.
  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • If you experience dry mouth, use sugarless candy or gum, or melt bits of ice in your mouth. If dry mouth continues for more than 2 weeks, contact your dentist or doctor.
  • Serotonin syndrome is a possibly fatal syndrome that can be caused by Flexeril. Your risk may be greater if you take Flexeril with certain other medicines (eg, "triptans," MAOIs, SSRIs). Symptoms may include agitation, confusion, hallucinations, coma, fever, fast or irregular heartbeat, tremor, excessive sweating, nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
  • Use Flexeril with extreme caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, hallucinations, and fast or irregular heartbeat.
  • Flexeril should be used with extreme caution in CHILDREN younger than 15 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Flexeril while you are pregnant. It is not known if Flexeril is found in breast milk. If you are or will be breast-feeding while you use Flexeril, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Flexeril:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth; fatigue; nausea; nervousness; stomach pain or upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; confusion; fainting; fast or irregular heartbeat; mental or mood changes; numbness of an arm or a leg; one-sided weakness; seizures; sudden severe stomach pain; severe dizziness or vomiting; speech or vision problems; trouble urinating; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; chest pain; coma; confusion; fast or irregular heartbeat; loss of coordination; hallucinations; seizures; severe drowsiness, dizziness, or headache; slurred speech; tremor; vomiting.

Proper storage of Flexeril:

Store Flexeril at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Flexeril out of the reach of children and away from pets.

General information:

  • If you have any questions about Flexeril, please talk with your doctor, pharmacist, or other health care provider.
  • Flexeril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Flexeril or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Flexeril. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Flexeril. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Flexeril.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Hide
(web1)