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Doryx delayed-release capsules

Pronunciation

Generic Name: doxycycline hyclate (DOX-i-SYE-kleen HYE-klate)
Brand Name: Doryx

Doryx delayed-release capsules is used for:

Treating certain bacterial infections. It may be used in combination with other medicines to treat acne or certain amoeba infections. It may be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months. It may also be used to prevent or slow the progression of anthrax after exposure.

Doryx delayed-release capsules is a tetracycline antibiotic. It works by slowing the growth of bacteria. Slowing the bacteria's growth allows the body's immune system to destroy the bacteria.

Do NOT use Doryx delayed-release capsules if:

  • you are allergic to any ingredient in Doryx delayed-release capsules or to any other tetracycline antibiotic (eg, minocycline)
  • you are taking acitretin, methoxyflurane, isotretinoin, or a penicillin (eg, amoxicillin)
  • you have recently received or will be receiving a live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Flashback: FDA Drug Approvals 2013

Before using Doryx delayed-release capsules:

Some medical conditions may interact with Doryx delayed-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a stomach infection, or the blood disease porphyria
  • if you have a history of lupus

Some MEDICINES MAY INTERACT with Doryx delayed-release capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or iron because they may decrease Doryx delayed-release capsules's effectiveness
  • Acitretin, anticoagulants (eg, warfarin), digoxin, isotretinoin, methotrexate, or methoxyflurane because the risk of their side effects may be increased by Doryx delayed-release capsules
  • Live oral typhoid vaccine, hormonal birth control (eg, birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Doryx delayed-release capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Doryx delayed-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Doryx delayed-release capsules:

Use Doryx delayed-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Doryx delayed-release capsules by mouth with or without food. If stomach upset occurs, take with food or milk to reduce stomach irritation.
  • Swallow Doryx delayed-release capsules whole. Do not break, crush, or chew before swallowing.
  • Drink plenty of fluids with Doryx delayed-release capsules to wash it down. This will also help to decrease the risk of throat irritation from Doryx delayed-release capsules.
  • If you cannot swallow the capsule whole, you may open it and sprinkle the contents over a spoonful of applesauce. Do not use hot applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. Do not crush or chew the medicine before swallowing. Do not store the mixture for future use.
  • Do not take an antacid that has aluminum, magnesium, or calcium in it; sodium bicarbonate; or bismuth salts (eg, bismuth subsalicylate) within 2 hours of taking Doryx delayed-release capsules.
  • To clear up your infection completely, take Doryx delayed-release capsules for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you are taking Doryx delayed-release capsules to prevent malaria, you should begin to take it 1 to 2 days before you travel to the malaria-infected area. You will need to keep taking it for 4 weeks after you leave the area. Discuss any questions with your doctor.
  • Do not use Doryx delayed-release capsules if it is outdated or has been stored incorrectly.
  • If you miss a dose of Doryx delayed-release capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Doryx delayed-release capsules.

Important safety information:

  • Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Be sure to use Doryx delayed-release capsules for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Doryx delayed-release capsules only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Doryx delayed-release capsules may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • If you are taking Doryx delayed-release capsules to prevent malaria, please note that no malaria medicine, including Doryx delayed-release capsules, guarantees protection against malaria. Stay in well-screened areas, use mosquito nets, cover the body with clothing, and use insect repellant to avoid being bitten by mosquitoes.
  • Doryx delayed-release capsules may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doryx delayed-release capsules. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or blood stools occur. Do not treat diarrhea without first checking with your doctor.
  • Tell your doctor or dentist that you take Doryx delayed-release capsules before you receive any medical or dental care, emergency care, or surgery.
  • Doryx delayed-release capsules may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Doryx delayed-release capsules.
  • Doryx delayed-release capsules should not be used in CHILDREN younger than 8 years old; permanent yellow-gray-brown tooth discoloration may occur.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Doryx delayed-release capsules. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • PREGNANCY and BREAST-FEEDING: Doryx delayed-release capsules has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doryx delayed-release capsules while you are pregnant. Doryx delayed-release capsules is found in breast milk. Do not breast-feed while taking Doryx delayed-release capsules.

Possible side effects of Doryx delayed-release capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Loss of appetite; nausea; sensitivity to sunlight; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; red, swollen, blistered, or peeling skin; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Doryx delayed-release capsules:

Store Doryx delayed-release capsules at or below 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Doryx delayed-release capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Doryx delayed-release capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Doryx delayed-release capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Doryx delayed-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Doryx delayed-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Doryx delayed-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Doryx delayed-release capsules.

Issue Date: December 3, 2014
Database Edition 14.4.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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