Diethylpropion

Pronunciation

Generic Name: diethylpropion (dye-eth-il-PROE-pee-on)
Brand Name: Tenuate

Diethylpropion is used for:

Short-term weight reduction in the management of obesity as part of a diet plan, exercise, and behavior therapy.

Diethylpropion is an appetite suppressant. It works by acting on the appetite center in the brain to cause a temporary reduction in hunger or craving for food.

Do NOT use diethylpropion if:

  • you are allergic to any ingredient in diethylpropion
  • you are currently taking guanadrel, guanethidine, furazolidone, or other weight loss medicines
  • you are currently taking or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days
  • you have a history of heart disease, atherosclerosis, brain or spinal cord disorders, high blood pressure in the lungs, severe or uncontrolled high blood pressure, an overactive thyroid, glaucoma, a highly nervous state or agitation, or a history of substance abuse

Contact your doctor or health care provider right away if any of these apply to you.

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Before using diethylpropion:

Some medical conditions may interact with diethylpropion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems, diabetes, high blood pressure, blood vessel disease, irregular heartbeat or other heart problems, or a history of seizures
  • if you have used weight loss medicines within the last year

Some MEDICINES MAY INTERACT with diethylpropion. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Furazolidone, MAO inhibitors (eg, phenelzine), general anesthetics (eg, thiopental), or tramadol because side effects such as elevated blood pressure, slow or irregular heartbeat, elevated body temperature, or an increased risk of seizures may occur
  • Serotonin reuptake inhibitors (eg, fluoxetine) because the actions and side effects of these medicines may be increased
  • Guanethidine and methyldopa because the effectiveness of these medicines may be decreased
  • Phenothiazines (eg, thioridazine) because the effectiveness of diethylpropion may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if diethylpropion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use diethylpropion:

Use diethylpropion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take diethylpropion 1 hour before meals. If desired, take it at least 4 to 6 hours before bedtime to avoid night hunger, or as directed by your doctor.
  • If you miss a dose of diethylpropion, take it as soon as possible. If it is after 4 pm, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use diethylpropion.

Important safety information:

  • Diethylpropion may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to diethylpropion.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking diethylpropion. Diethylpropion will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Do not use diethylpropion with any other weight loss medicines, including over-the-counter, prescription, or herbal/natural supplements.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are taking diethylpropion.
  • It is dangerous and illegal to use diethylpropion to improve athletic skills, mental alertness, or to stay awake.
  • Diabetes patients - Diethylpropion may affect your blood sugar level. Your doctor may need to adjust the dose of diabetes medicine you are taking.
  • Use diethylpropion with caution in the ELDERLY because they may be more sensitive to its effects.
  • Diethylpropion is not recommended for CHILDREN younger than 16 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using diethylpropion during pregnancy. Diethylpropion is excreted in breast milk. If you are or will be breast-feeding while you are using diethylpropion, check with your doctor or pharmacist to discuss the risks to your baby.

Diethylpropion may be habit-forming and has the potential for abuse. Stopping diethylpropion suddenly can cause symptoms of WITHDRAWAL, including extreme tiredness, depression, and sleep changes. Do not stop taking diethylpropion suddenly. If you feel that your medicine is not working any more, talk with your doctor. Do not take more medicine or use it for a longer period of time than prescribed.

Possible side effects of diethylpropion:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; bad taste in mouth; change in sex drive; constipation; depression; diarrhea; difficulty moving; dizziness; drowsiness; dry mouth; enlargement of breasts; exaggerated sense of well-being; general body discomfort; hair loss; headache; increased pupil size; increased urination; jitteriness; menstrual upset; nausea; nervousness; restlessness; sleeplessness; stomach upset; tremor; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; blurred vision; chest pain; chills; fainting; fast or irregular heartbeat; fever; impotence; painful urination; pounding in the chest; seizures; shortness of breath; sore throat; swelling of the legs and feet; unusual bruising.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include aggressiveness; changes in heartbeat; confusion; diarrhea; excessive sweating; fainting; hallucinations; large pupil size; nausea; pounding in the chest; panic states; rapid breathing; restlessness; stomach cramps; tremor; vomiting.

Proper storage of diethylpropion:

Store diethylpropion at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep diethylpropion out of the reach of children and away from pets.

General information:

  • If you have any questions about diethylpropion, please talk with your doctor, pharmacist, or other health care provider.
  • Diethylpropion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take diethylpropion or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about diethylpropion. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to diethylpropion. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using diethylpropion.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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