Skip to main content

Zoto-HC Drops Side Effects

Generic name: chloroxylenol / hydrocortisone / pramoxine otic

Medically reviewed by Drugs.com. Last updated on Apr 1, 2024.

Note: This document contains side effect information about chloroxylenol / hydrocortisone / pramoxine otic. Some dosage forms listed on this page may not apply to the brand name Zoto-HC Drops.

Applies to chloroxylenol / hydrocortisone / pramoxine otic: otic lotion, otic solution.

Medicinal use of this product to treat ear infections has not been approved by the FDA.

You should not use this medicine if you have a hole in your ear drum (ruptured ear drum), or if you also have chickenpox or cowpox.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when this medicine is used in the ears, side effects can occur if hydrocortisone is absorbed into your bloodstream.

Steroid medicine absorbed through the skin inside your ears can cause steroid side effects throughout the body, such as: thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

Stop using this medicine and call your doctor at once if you have severe burning or other irritation after using the ear drops.

Common side effects may include mild stinging or burning with the first use.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

More about Zoto-HC Drops (chloroxylenol / hydrocortisone / pramoxine otic)

Patient resources

Other brands

Pramox-HC, Exotic-HC, Aero Otic HC, Cortane-B, ... +3 more

Related treatment guides

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.