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Vaccinia immune globulin Side Effects

Applies to vaccinia immune globulin: intravenous solution

As well as its needed effects, vaccinia immune globulin may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking vaccinia immune globulin, check with your doctor immediately:

Incidence unknown
  • Fever
  • headache
  • nausea
  • stiff neck or back
Observed postmarketing
  • Back, leg or stomach pain
  • black, tarry stools
  • bleeding gums
  • blistering, peeling, loosening of skin
  • bluish color of fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • change in consciousness
  • chest pain
  • chills
  • cold, clammy, pale skin
  • confusion
  • convulsions
  • cough
  • coughing that produces a pink frothy sputum
  • dark urine
  • decreased urination
  • diarrhea
  • difficulty or labored breathing
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • fatigue
  • general body swelling
  • itching
  • irregular heartbeats
  • joint or muscle pain
  • light-colored stools
  • loss of appetite
  • loss of bladder control
  • loss of consciousness
  • muscle spasms or jerking of all extremities
  • nausea or vomiting
  • no blood pressure or pulse
  • noisy breathing
  • nosebleeds
  • not breathing
  • pain in chest, groin, or legs, especially the calves
  • painful or difficult urination
  • red irritated eyes
  • red skin lesions, often with a purple center
  • severe, sudden headache
  • severe weakness or numbness in arm or leg
  • shortness of breath
  • slow heart rate
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots in mouth or on lips
  • stopping of heart
  • sudden loss of coordination
  • suddenly sweating
  • swelling in legs and ankles
  • swollen glands
  • tightness in chest
  • troubled breathing
  • unconsciousness
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vision changes
  • wheezing
  • yellowing of the eyes or skin

Minor Side Effects

Some vaccinia immune globulin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • eye disorder
  • energy increased
  • feeling unusually cold
  • feeling hot
  • lack or loss of strength
  • lip dry
  • muscle pain
  • shakiness in legs, arms, hands, feet
  • shivering
  • trembling or shaking of hands or feet

It is possible that some side effects of vaccinia immune globulin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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