Lucinactant Side Effects
Medically reviewed by Drugs.com. Last updated on Feb 20, 2025.
Applies to lucinactant: intratracheal suspension.
Precautions
It is very important that your child's doctor check your child's progress closely while receiving the medicine. This will allow the doctor to see if the medicine is working properly and to decide if your child should continue to receive it.
Serious side effects of lucinactant
Along with its needed effects, lucinactant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking lucinactant:
More common side effects
- bluish lips or skin
- cough
- coughing up blood
- fast heartbeat
- fever or chills
- pale skin
- rapid, shallow breathing
- shortness of breath
- slow heartbeat
- sneezing
- troubled breathing
- wheezing
Incidence not known
- blue or white in color
- heart may stop
- no oxygen to lungs
- patient unresponsive
Other side effects of lucinactant
Some side effects of lucinactant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
For healthcare professionals
Applies to lucinactant: intratracheal suspension.
Cardiovascular adverse events
- Very common (10% or more): Patent ductus arteriosus (up to 43%), hypotension (at least 10%), bradycardia (at least 10%)
- Common (1% to 10%): Pallor (up to 10%)[Ref]
Gastrointestinal
- Very common (10% or more): Necrotizing enterocolitis (up to 17%)[Ref]
Hematologic
Hepatic
- Very common (10% or more): Jaundice (at least 10%)
Metabolic
- Very common (10% or more): Metabolic acidosis (at least 10%), hyperglycemia (at least 10%), hyponatremia (at least 10%)[Ref]
Nervous system
- Very common (10% or more): Intraventricular hemorrhage (up to 52%)
- Common (1% to 10%): Periventricular leukomalacia (up to 10%)[Ref]
Ocular
- Very common (10% or more): Retinopathy of prematurity (up to 32%)[Ref]
Other
- Very common (10% or more): Acquired sepsis (up to 45%)
Respiratory
- Very common (10% or more): Apnea (up to 66%), endotracheal tube reflux (up to 27%), endotracheal tube obstruction (up to 16%), pulmonary air leak (up to 15%), oxygen desaturation (at least 10%), pneumonia (at least 10%)
- Common (1% to 10%): Pulmonary hemorrhage (up to 10%), respiratory acidosis (up to 10%), pulmonary interstitial emphysema (up to 9%), pneumothorax (up to 4%)[Ref]
See also:
Ozempic
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Calfactant
Calfactant systemic is used for respiratory distress syndrome
References
1. (2012) "Product Information. Surfaxin (lucinactant)." Discovery Laboratories Inc
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Further information
Lucinactant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.