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Haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine Side Effects

Medically reviewed by Last updated on Aug 25, 2021.

For the Consumer

Applies to haemophilus b conjugate (prp-t) vaccine/meningococcal conjugate vaccine: intramuscular solution reconstituted

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child's doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Trouble controlling body movements.
  • Not able to move face muscles as much.
  • Muscle weakness.
  • Change in eyesight.
  • A burning, numbness, or tingling feeling that is not normal.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child's doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

  • Pain where the shot was given.
  • Redness or swelling where the shot is given.
  • Feeling fussy.
  • Feeling sleepy.
  • Not hungry.
  • Fever.

These are not all of the side effects that may occur. If you have questions about side effects, call your child's doctor. Call your child's doctor for medical advice about side effects.

For Healthcare Professionals

Applies to haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine: intramuscular powder for injection

Nervous system

Very common (10% or more): Drowsiness

Postmarketing reports: Febrile seizures, hypotonia, headache, dizziness[Ref]


Very common (10% or more): Fever (rectal 38C or higher)

Uncommon (0.1% to 1%): Fever (rectal over 39.5C)

Rare (less than 0.1%): Malaise[Ref]


Very common (10% or more): Decreased appetite[Ref]


Very common (10% or more): Injection site reaction (swelling, pain, redness)

Common (1% to 10%): Injection site reactions including induration and nodules[Ref]


Very common (10% or more): Irritability

Uncommon (0.1% to 1%): Crying

Rare (less than 0.1%): Insomnia[Ref]


Postmarketing reports: Apnea in very premature infants (28 weeks gestation or less)[Ref]


Uncommon (0.1% to 1%): Diarrhea, vomiting

Rare (less than 0.1%): Abdominal pain[Ref]


Uncommon (0.1% to 1%): Atopic dermatitis, rash[Ref]


Postmarketing reports: Lymphadenopathy[Ref]


Postmarketing reports: Allergic reactions (including urticaria and anaphylactoid reactions)[Ref]

More about haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine

Consumer resources

Other brands

Related treatment guides


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.