Golodirsen Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 19, 2025.

Applies to golodirsen: intravenous solution.

Precautions

Your child's doctor will check your child's progress closely while your child is receiving this medicine. This will allow your child's doctor to see if the medicine is working properly and to decide if your child should continue to receive it.

Serious allergic reactions may occur while your child is receiving this medicine. Tell your child's doctor right away if your child has a fever, hives or rash, blistering, crusting, itching, or reddening of the skin, trouble breathing or swallowing, or unusual tiredness or weakness.

Serious side effects of golodirsen

Along with its needed effects, golodirsen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking golodirsen:

Other side effects of golodirsen

Some side effects of golodirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to golodirsen: intravenous solution.

General adverse events

The most commonly reported adverse reactions have included headache, pyrexia, falls, abdominal pain, nasopharyngitis, cough, vomiting, and nausea.^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions

Nervous system

• Very common (10% or more): Headache (41%)
• Common (1% to 10%): Dizziness

Gastrointestinal

• Very common (10% or more): Abdominal pain (27%), vomiting (27%), nausea (20%)
• Common (1% to 10%): Diarrhea, oropharyngeal pain, constipation

Local

• Common (1% to 10%): Administration site pain, catheter site related reaction

Immunologic

• Common (1% to 10%): Influenza, seasonal allergy

Musculoskeletal

• Common (1% to 10%): Back pain, ligament strain, fracture

Respiratory

• Very common (10% or more): Nasopharyngitis (27%)
• Common (1% to 10%): Rhinitis

Other

• Very common (10% or more): Pyrexia (41%), fall (29%)
• Common (1% to 10%): Pain, ear infection

Cardiovascular

• Common (1% to 10%): Tachycardia

Dermatologic

• Common (1% to 10%): Contusion, skin abrasion

See also:

Further information

Golodirsen side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer