Evrysdi Side Effects
Generic name: risdiplam
Medically reviewed by Drugs.com. Last updated on Oct 30, 2021.
Note: This document contains side effect information about risdiplam. Some of the dosage forms listed on this page may not apply to the brand name Evrysdi.
For the Consumer
Applies to risdiplam: oral powder for solution
Side effects requiring immediate medical attention
Along with its needed effects, risdiplam (the active ingredient contained in Evrysdi) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking risdiplam:
- Body aches or pain
- chest pain or tightness
- ear congestion
- loss of voice
- runny or stuffy nose
- sore throat
- trouble breathing
- unusual tiredness or weakness
- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
Side effects not requiring immediate medical attention
Some side effects of risdiplam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Canker sores
- skin rash
- sores, ulcers, or white spots on the lips or tongue or inside the mouth
- Difficulty in moving
- joint pain
- muscle pain or stiffness
For Healthcare Professionals
Applies to risdiplam: oral powder for reconstitution
The most reported adverse events have included fever, diarrhea, and rash; additionally, among patients with infantile-onset spinal muscular atrophy, upper respiratory tract infection, pneumonia, constipation, and vomiting were reported.[Ref]
Very common (10% or more): Diarrhea (17%), constipation, vomiting
Common (1% to 10%): Mouth and aphthous ulcers
Very common (10% or more): Fever (22%)
Very common (10% or more): Rash (17%)
Rash includes reports of rash, erythema, rash maculo-papular, rash erythematous, rash popular, dermatitis allergic, and folliculitis.
Respiratory tract infection includes reports of nasopharyngitis, rhinitis, and respiratory tract infection.
Very common (10% or more): Upper respiratory tract infection, pneumonia
Common (1% to 10%): Arthralgia
Common (1% to 10%): Urinary tract infection
Frequently asked questions
- Evrysdi vs Spinraza: How do they compare?
- How does it work for SMA?
- How effective is it?
- Does it cure spinal muscular atrophy (SMA)?
- How is it administered?
More about Evrysdi (risdiplam)
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous uncategorized agents
- FDA Approval History
Related treatment guides
1. "Product Information. Evrysdi (risdiplam)." Genentech, South San Francisco, CA.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.