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Cysto-Conray Side Effects

Generic Name: iothalamate

Note: This page contains information about the side effects of iothalamate. Some of the dosage forms included on this document may not apply to the brand name Cysto-Conray.

Applies to iothalamate: injectable solution

Dermatologic

Common (1% to 10%): Pruritus, urticarial, face edema
Uncommon (0.1% to 1%): Erythema, rash
Rare (less than 0.1%): Angioedema, diaphoresis
Frequency not reported: Ecchymosis and tissue necrosis[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting
Rare (0.01% to 0.1%): Diarrhea, dry mouth, tongue edema
Very rare (less than 0.01%): Dysphagia[Ref]

Hypersensitivity

Common (1% to 10%): Anaphylactoid reactions
Frequency not reported: Dermal manifestations (urticaria with or without pruritus, erythema, maculopapular rash); dry mouth, sweating, conjunctival symptoms; facial, peripheral, and angioneurotic edema; symptoms related to the respiratory system include sneezing, nasal stuffiness, coughing, choking, dyspnea, chest tightness and wheezing, which may be initial manifestations of more severe and infrequent reactions including asthmatic attack, laryngospasm and bronchospasm with or without edema, pulmonary edema, apnea and cyanosis[Ref]

Rarely, these allergic-type reactions can progress into anaphylaxis with loss of consciousness and coma and severe cardiovascular disturbances.[Ref]

Respiratory

Common (1% to 10%): Rhinitis
Uncommon (0.1% to 1%): Coughing, dyspnea
Rare (0.01% to 0.1%): Larynx edema
Very rare (less than 0.01%): Apnea, bronchospasm[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Hypotension
Rare (0.01% to 0.1%): Thrombophlebitis, tachycardia, ventricular fibrillation, pallor, vasodilation, cyanosis
Very rare (less than 0.01%): Disseminated intravascular coagulation resulting in death; arrhythmia; bradycardia; cardiac arrest, circulatory failure; abnormal ECG; heart block; phlebitis
Frequency not reported: Generalized vasodilation, flushing and venospasm; occasionally thrombosis; severe cardiovascular responses include rare cases of hypotensive shock, coronary insufficiency, cardiac arrhythmia, fibrillation and arrest; extravasation with burning pain; hematomas; vascular constriction due to injection rate; thrombosis[Ref]

These severe reactions are usually reversible with prompt and appropriate management; however, fatalities have occurred.[Ref]

Endocrine

Uncommon (0.1% to 1%): Thyroid function tests indicative of hypothyroidism or transient thyroid suppression in adults and pediatric patients (including infants)[Ref]

Ocular

Uncommon (0.1% to 1%): Periorbital edema
Rare (0.01% to 0.1%): Conjunctivitis
Very rare (less than 0.01%): Vision disorders[Ref]

Local

Rare (less than 0.1%): Injection side reaction[Ref]

Nervous system

Rare (0.01% to 0.1%): Dizziness; paraesthesia; taste perversion
Very rare (less than 0.01%): Agitation, coma, convulsions, dyskinesia, paralysis, tremor, somnolence
Frequency not reported: Aphasia; syncope, paresis; paralysis resulting from spinal cord injury and pathology associated with syndrome of transverse myelitis; visual field losses which are usually transient but may be permanent; coma and death; headache, trembling, shaking, numbness[Ref]

Genitourinary

Very rare (less than 0.01%): Urinary incontinence[Ref]

Metabolic

Very rare (less than 0.01%): Thirst[Ref]

Musculoskeletal

Very rare (less than 0.01%): Involuntary muscle contractions, myalgia, leg pain
Frequency not reported: Spasm[Ref]

Other

Very common (10% or more): Hot flushes, pain
Rare (0.01% to 0.1%): Malaise
Very rare (less than 0.01%): Edema, abnormal crying
Frequency not reported: Chills without fever and lightheadedness[Ref]

Psychiatric

Very rare (less than 0.01%): Anxiety[Ref]

Renal

Very rare (less than 0.01%): Acute renal failure, decrease in renal function
Frequency not reported: Temporary renal shutdown or other nephropathy[Ref]

Hematologic

Frequency not reported: Red blood cell clumping and agglutination, crenation and interference in clot formation[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Conray (iothalamate)." Mallinckrodt Medical Inc, St. Louis, MO.

3. Cerner Multum, Inc. "Australian Product Information." O 0

Not all side effects for Cysto-Conray may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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