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Trypan blue ophthalmic Pregnancy and Breastfeeding Warnings

Brand names: MembraneBlue, VisionBlue

Trypan blue ophthalmic Pregnancy Warnings

This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.

US FDA pregnancy category: C

Animal studies have revealed evidence of fetal anomalies (e.g., cardiovascular, eye, neural tube, tail, and/or vertebral defects), increased post-implantation mortality, decreased fetal weight, and increased abortions in single, IV, intraperitoneal, or subcutaneous doses of 25 to 50 mg/kg administered during embryogenesis. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Trypan blue ophthalmic Breastfeeding Warnings

Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comment: The effects in the nursing infant are unknown.

See references

See also

References for pregnancy information

  1. Product Information. VisionBlue (trypan blue ophthalmic). Dutch Ophthalmic USA. 2006.
  2. Product Information. MembraneBlue (trypan blue ophthalmic). Dutch Ophthalmic USA. 2017.

References for breastfeeding information

  1. Product Information. VisionBlue (trypan blue ophthalmic). Dutch Ophthalmic USA. 2006.
  2. Product Information. MembraneBlue (trypan blue ophthalmic). Dutch Ophthalmic USA. 2017.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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