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Phendimetrazine Pregnancy and Breastfeeding Warnings

Phendimetrazine is also known as: Adipost, Anorex-SR, Appecon, Bontril PDM, Bontril Slow Release, Melfiat, Obezine, Phendiet, Phendiet-105, Plegine, Prelu-2, Prelu-2 TR, Statobex

Medically reviewed by Last updated on Jul 26, 2018.

Phendimetrazine Pregnancy Warnings

-Extended-release: This drug is contraindicated during pregnancy.
-Immediate-release: Safety has not been established during pregnancy; this drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus.

US FDA pregnancy category: X (extended-release)
US FDA pregnancy category: C (immediate-release)

Comments: Animal reproduction and fertility studies have not been conducted with this drug.

US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Phendimetrazine Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: This drug has pharmacological activity similar to the amphetamines; amphetamines are present in human milk.

See references

References for pregnancy information

  1. "Product Information. Prelu-2 (phendimetrazine)" Boehringer-Ingelheim, Ridgefield, CT.

References for breastfeeding information

  1. "Product Information. Prelu-2 (phendimetrazine)" Boehringer-Ingelheim, Ridgefield, CT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.