Skip to Content
How to use eye drops. Find out more here >

Pegaptanib ophthalmic Pregnancy and Breastfeeding Warnings

Pegaptanib ophthalmic is also known as: Macugen

Pegaptanib ophthalmic Pregnancy Warnings

Use during pregnancy only if clearly needed. US FDA pregnancy category: B Comments: This drug crosses the placenta in animals.

Animal studies did not reveal evidence of teratogenicity, fetal mortality, or maternal toxicity at IV doses of up to 40 mg/kg/day (about 7000 times the recommended human dose). No information is available to evaluate the drug effect on mating or fertility. There are no controlled data in human pregnancy. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Pegaptanib ophthalmic Breastfeeding Warnings

Use with caution during breastfeeding. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Macugen (pegaptanib ophthalmic)." OSI Pharmaceuticals Inc, Melville, NY.

References for breastfeeding information

  1. "Product Information. Macugen (pegaptanib ophthalmic)." OSI Pharmaceuticals Inc, Melville, NY.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide