Netarsudil ophthalmic Pregnancy and Breastfeeding Warnings

Brand names: Rhopressa

Medically reviewed by Drugs.com. Last updated on Apr 30, 2024.

Netarsudil ophthalmic Pregnancy Warnings

The manufacturer makes no recommendation regarding use during pregnancy.

US FDA pregnancy category: Not assigned.

Risk Summary: No data available on use of this drug in pregnant women to inform a drug-related risk.

Comments: Systemic absorption is low following ocular administration.

Animal studies have not been reported. Animal studies with the IV formulation to pregnant rats and rabbits during organogenesis did not produce adverse embryofetal effects at clinically relevant systemic exposures. When administered IV at higher doses, abortions, embryofetal lethality, and decreased fetal weight were observed. There are no controlled data in human pregnancy.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

See references

Netarsudil ophthalmic Breastfeeding Warnings

The manufacturer makes no recommendation regarding use during lactation.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-Systemic exposure to this drug is low following topical ocular administration and it is unknown whether measurable levels would be present in maternal milk.
-Developmental and health benefits of breastfeeding should be considered as well as the mother's clinical need for this drug.
-Potential side effects in the breastfed child due to the drug or the mother's underlying condition should be considered.

See references

Further information

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