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Hydroxocobalamin Pregnancy and Breastfeeding Warnings

Hydroxocobalamin is also known as: Cobalin-H, Cyanokit, Hydro-Cobex, Hydroxy-Cobal, Neo-Cytamen

Medically reviewed on February 13, 2018

Hydroxocobalamin Pregnancy Warnings

Hydroxocobalamin has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. The manufacturer states hydroxocobalamin is only recommended for use during pregnancy when benefit outweighs risk. However, there are reports which suggest severe maternal Vitamin B12 deficiency may result in infertility and/or poor pregnancy outcome as a result of megaloblastic anemia. Less severe maternal deficiency may be common in the course of pregnancy and usually does not pose a risk to mother or fetus. Many sources recommend Vitamin B12 therapy during pregnancy up to the RDA.

See references

Hydroxocobalamin Breastfeeding Warnings

Hydroxocobalamin is excreted into human milk. Hydroxocobalamin is considered compatible with breast-feeding by the American Academy of Pediatrics

See references

References for pregnancy information

  1. "Product Information. Hydro-Cobex (hydroxocobalamin)." Major Pharmaceuticals Inc, Rosemont, IL.
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  2. "Product Information. Hydro-Cobex (hydroxocobalamin)." Major Pharmaceuticals Inc, Rosemont, IL.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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