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Hydrocortisone / neomycin / polymyxin b ophthalmic Pregnancy and Breastfeeding Warnings

Brand names: Cortisporin Ophthalmic Suspension, Cortomycin Suspension, Neo/PolyB/HC

Medically reviewed by Drugs.com. Last updated on Nov 18, 2024.

Hydrocortisone / neomycin / polymyxin b ophthalmic Pregnancy Warnings

This drug should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.

US FDA pregnancy category: C

Animal studies have not been reported. Corticosteroids have been found to be teratogenic in rabbits when applied topically at concentrations of 0.5% and 15%. There are no controlled data in human pregnancy.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Hydrocortisone / neomycin / polymyxin b ophthalmic Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: The effects in the nursing infant are unknown.

It is unknown whether topically administered corticosteroids could result in sufficient systemic absorption to produce detectable levels in breast milk; however, systemically administered corticosteroids may appear in breast milk and could suppress growth, interfere with endogenous corticosteroid production, or cause untoward effects.

See references

Does Hydrocortisone/neomycin/polymyxin b ophthalmic interact with my other drugs?

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References for pregnancy information

  1. "Product Information. Cortisporin Ophthalmic (bacitracin/hydrocortisone/neomycin/polymyxin B ophthalmic)." Allscrips Pharmaceutical Company

References for breastfeeding information

  1. "Product Information. Cortisporin Ophthalmic (bacitracin/hydrocortisone/neomycin/polymyxin B ophthalmic)." Allscrips Pharmaceutical Company
  2. United States National Library of Medicine (2013) Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.