Hydrochlorothiazide / metoprolol Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on Aug 25, 2022.
Hydrochlorothiazide / metoprolol is also known as: Dutoprol, Lopressor HCT
Hydrochlorothiazide / metoprolol Pregnancy Warnings
Animal studies have revealed evidence of decreased postnatal survival and increased postimplantation and fetal loss. There are no controlled data in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.
US FDA pregnancy category: C
Hydrochlorothiazide / metoprolol Breastfeeding Warnings
A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
Excreted into human milk: Yes (hydrochlorothiazide, metoprolol [in small amounts])
A mother taking metoprolol would transfer less than 1 mg/L to a breastfeeding infant.
See also
References for pregnancy information
- "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals (2022):
References for breastfeeding information
- "Product Information. Lopressor HCT (hydrochlorothiazide-metoprolol)." Novartis Pharmaceuticals (2022):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
