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Hepatitis a adult vaccine / hepatitis b adult vaccine Pregnancy and Breastfeeding Warnings

Hepatitis a adult vaccine / hepatitis b adult vaccine is also known as: Twinrix

Medically reviewed on December 12, 2017

Hepatitis a adult vaccine / hepatitis b adult vaccine Pregnancy Warnings

Hepatitis A-hepatitis B vaccine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. The vaccine is only recommended for use during pregnancy when clearly indicated. The Advisory Committee on Immunization Practices recommends vaccination of pregnant women at risk for hepatitis B infection.

A Twinrix Pregnancy Registry has been established to monitor maternal-fetal outcome of vaccine exposures during pregnancy. To register patients, physicians may call 888-452-9622 (USA).

See references

Hepatitis a adult vaccine / hepatitis b adult vaccine Breastfeeding Warnings

There are no data on the excretion of hepatitis A-hepatitis B vaccine into human milk. The manufacturer recommends that caution be used when administering the vaccine to nursing women. The U.S. Centers for Disease Control and Prevention (CDC) consider the administration of inactivated virus vaccines compatible with breast-feeding.

See references

References for pregnancy information

  1. "Product Information. Twinrix (hepatitis A-hepatitis B vaccine)" SmithKline Beecham, Philadelphia, PA.
  2. CDC. Centers for Disease Control and Prevention. "General recommendations on immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP)and the American Academy of Family Physicians (AAFP)." MMWR Morb Mortal Wkly Rep 51(RR-2) (2002): 1-35

References for breastfeeding information

  1. "Product Information. Twinrix (hepatitis A-hepatitis B vaccine)" SmithKline Beecham, Philadelphia, PA.
  2. CDC. Centers for Disease Control and Prevention. "General recommendations on immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP)and the American Academy of Family Physicians (AAFP)." MMWR Morb Mortal Wkly Rep 51(RR-2) (2002): 1-35
  3. CDC. Centers for Disease Control and Prevention. National Center for Infectious Diseases Travelor's Health "Pregnancy, breast-feeding, and travel: factors affecting the decision to travel. Available from: URL: http://www.cdc.gov/travel/pregnant.htm." ([2003 Jul 17]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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