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Ceftazidime Pregnancy and Breastfeeding Warnings

Ceftazidime is also known as: Ceptaz, Fortaz, Tazicef, Tazicef Novaplus, Tazidime

Ceftazidime Pregnancy Warnings

One uncontrolled study of pregnant women between 19 and 21 weeks gestation has suggested that ceftazidime serum concentrations are approximately 50% those expected in nonpregnant women.

Ceftazidime has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal any evidence of teratogenicity. There are no controlled data in human pregnancy. Ceftazidime should only be given during pregnancy when need has been clearly established.

See references

Ceftazidime Breastfeeding Warnings

Ceftazidime is excreted into human milk in small amounts. Ceftazidime is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that caution be used when administering ceftazidime to nursing women.

See references

References for pregnancy information

  1. Giamarellou H, Gazis J, Petrikkos G, et al "A study of cefoxitin, moxalactam, and ceftazidime kinetics in pregnancy." Am J Obstet Gynecol 147 (1983): 914-9
  2. Heikkila A, Erkkola R "Review of beta-lactam antibiotics in pregnancy - the need for adjustment of dosage schedules." Clin Pharmacokinet 27 (1994): 49-62
  3. "Product Information. Fortaz (ceftazidime)." Glaxo Wellcome, Research Triangle Park, NC.
  4. Nathorstboos J, Philipson A, Hedman A, Arvisson A "Renal elimination of ceftazidime during pregnancy." Am J Obstet Gynecol 172 (1995): 163-6

References for breastfeeding information

  1. Blanco JD, Jorgensen JH, Castaneda YS, Crawford SA "Ceftazidime levels in human breast milk." Antimicrob Agents Chemother 23 (1983): 479-80
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  3. "Product Information. Fortaz (ceftazidime)." Glaxo Wellcome, Research Triangle Park, NC.

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