Carboprost Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on Feb 23, 2023.
Carboprost is also known as: Hemabate
Carboprost Pregnancy Warnings
Carboprost does not appear to directly affect the placental unit; therefore, it is possible that a previable fetus aborted by carboprost could exhibit transient life signs. Studies in animals do not indicate teratogenicity; however, reproductive toxicity has been shown and any dose, which produces increased uterine tone, could put the embryo or fetus at risk.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
UK: Contraindicated
US: The manufacturer makes no recommendation regarding use during pregnancy.
US FDA pregnancy category: C
Comments:
-There are no clinical data on the effects of this drug on fertility.
-The benzyl alcohol excipient has been associated with a fatal "gasping syndrome" in premature infants.
Carboprost Breastfeeding Warnings
The manufacturer makes no recommendation regarding use during lactation.
Excreted into human milk: Data not available
Excreted into animal milk: Data not available
See also
References for pregnancy information
- "Product Information. Hemabate (carboprost)." Pharmacia and Upjohn (2001):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
References for breastfeeding information
- "Product Information. Hemabate (carboprost)." Pharmacia and Upjohn (2001):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.