Type 2 Diabetes Linked to Increased Risk for Colorectal Cancer
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Nov. 15, 2023 -- Type 2 diabetes is associated with an increased risk for colorectal cancer (CRC), with increased associations for those without colonoscopy screening and with smoking history, according to a study published online Nov. 14 in JAMA Network Open.
Thomas Lawler, Ph.D., from the University of Wisconsin Carbone Cancer Center in Madison, and colleagues conducted a cohort study using data from the prospective Southern Community Cohort Study to examine whether diabetes is associated with CRC risk among understudied populations. Data were included for 54,597 participants (66 percent African American; 53 percent with income <$15,000 per year).
The researchers found that 289 of 25,992 participants with diabetes and 197 of 28,605 without diabetes developed CRC. Diabetes was associated with an elevated risk for CRC (hazard ratio, 1.47). Among participants without colonoscopy screening and those with smoking history, greater associations were seen (hazard ratios, 2.07 and 1.62, respectively), possibly due to differences in cancer screening. Participants with recent diabetes diagnoses also had greater associations (diabetes duration less than five versus five to 10 years: hazard ratio, 2.55), possibly due to recent cancer screening.
"Increased interactions with the health care system following a diabetes diagnosis, including increased referrals to CRC screening, may be important for mitigating the harm of diabetes-related metabolic dysfunction, particularly in early diabetes, on CRC risk," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted November 2023
Read this next
Researchers Quantify the Risk for Diabetes After Gestational Diabetes
THURSDAY, May 9, 2024 -- Gestational diabetes is associated with an increased risk for subsequent diabetes, with higher risk for gestational diabetes in second pregnancy and in...
Risk for Colorectal Cancer Is Low for Uncomplicated Diverticulitis
TUESDAY, May 7, 2024 -- The prevalence of colorectal cancer (CRC) is low for patients undergoing colonoscopy after an episode of uncomplicated diverticulitis, according to a study...
Exposure to Food Additive Emulsifiers Linked to Risk for Type 2 Diabetes
MONDAY, May 6, 2024 -- Exposure to food additive emulsifiers is associated with an increased risk for type 2 diabetes, according to a study published in the May issue of The...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.