Preoxygenation With Noninvasive Ventilation Yields Lower Hypoxemia
By Elana Gotkine HealthDay Reporter
FRIDAY, June 14, 2024 -- For critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation results in lower incidence of hypoxemia than preoxygenation with an oxygen mask, according to a study published online June 13 in the New England Journal of Medicine to coincide with the annual Critical Care Reviews Meeting, held from June 12 to 14 in Belfast, Northern Ireland.
Kevin W. Gibbs, M.D., from the Wake Forest School of Medicine in Winston-Salem, North Carolina, and colleagues conducted a multicenter, randomized trial at 24 emergency departments and intensive care units in the United States involving critically ill adults undergoing tracheal intubation. Participants were randomly assigned to receive preoxygenation with either noninvasive ventilation or an oxygen mask (624 and 637 patients, respectively).
The researchers found that hypoxemia occurred in 9.1 and 18.5 percent of patients in the noninvasive-ventilation and oxygen-mask groups, respectively. Cardiac arrest occurred in one and seven patients (0.2 versus 1.1 percent) in the noninvasive-ventilation and oxygen-mask groups, respectively. Aspiration occurred in six and nine patients (0.9 and 1.4 percent) in the noninvasive-ventilation and oxygen-mask groups, respectively.
"These findings have important clinical implications because hypoxemia during intubation is associated with cardiac arrest and death, and in current clinical care worldwide, most critically ill adults receive preoxygenation with an oxygen mask rather than with noninvasive ventilation," the authors write.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted June 2024
Read this next
Methotrexate Noninferior to Prednisone in Pulmonary Sarcoidosis
TUESDAY, May 20, 2025 -- For patients with pulmonary sarcoidosis, methotrexate is noninferior to prednisone with regard to the change from baseline to week 24 in the percentage of...
Use of Composite Allocation Score for Lung Transplant Wait List Improves Outcomes
MONDAY, May 19, 2025 -- Wait-list outcomes for lung transplants have substantially improved in the composite allocation score (CAS) era, according to a study presented at the...
Exposure to Smoke Pollution Ups Risk for Hospitalization for Respiratory Disease
FRIDAY, May 2, 2025 -- For older adults in the Western United States, exposure to high levels of smoke pollution is associated with an increase in hospitalizations for respiratory...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.