Overall Risk of Death Not Increased With Premenstrual Disorders
By Elana Gotkine HealthDay Reporter
WEDNESDAY, May 29, 2024 -- Women with premenstrual disorders (PMD) do not have increased risk of early death overall, but the risks of suicide and the risks for women with diagnosis before 25 years are elevated, according to a study published online May 28 in JAMA Network Open.
Marion Opatowski, Ph.D., from the Institute of Environmental Medicine at the Karolinska Institutet in Stockholm, and colleagues examined the associations of PMDs with overall and cause-specific mortality in a nationwide, population-based matched cohort study. Participants included women of reproductive age, with a first diagnosis of PMD between Jan. 1, 2001, and Dec. 31, 2018; 67,748 women with clinically diagnosed PMDs were matched with 338,740 unaffected women.
The researchers found that there were 367 deaths among women with PMDs during a mean follow-up of 6.2 years, and 1,958 deaths among women without PMDs (rates, 8.4 and 9.1 deaths, respectively, per 10,000 person-years). Women with PMDs had increased risk of death due to non-natural causes, especially suicide, compared with unaffected women (hazard ratios, 1.59 and 1.92, respectively), but did not have an increased risk of overall mortality. Higher all-cause mortality and mortality from both suicide and natural causes were seen for women who received a diagnosis before age 25 years (hazard ratios, 2.51, 3.84, and 2.59, respectively).
"This supports the importance of careful follow-up for young women with PMDs and highlights the need to develop suicide prevention strategies for all women with PMDs," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted May 2024
Read this next
Gabapentinoids Not Directly Associated With Risk of Self-Harm
THURSDAY, May 15, 2025 -- Gabapentinoids are not associated with risk of self-harm in adults; however, elevated risk is seen before initiation of treatment, during the initial...
Diet Quality Plays Role in Age at Menarche
MONDAY, May 12, 2025 -- Eating a healthy diet as a child is linked to girls having their first menstrual period at an older age than those who consume a less healthy diet...
Prior Military Sexual Trauma Linked to Late-Life Suicide Attempt
THURSDAY, May 1, 2025 -- Prior military sexual trauma (MST) is associated with late-life suicide attempt and death by suicide or overdose, according to a study published online...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.