Nearly One in Four Do Not Recover From COVID-19 by 90 Days
By Lori Solomon HealthDay Reporter
WEDNESDAY, June 19, 2024 -- Just under one-quarter of adults with self-reported COVID-19 report they had not recovered by 90 days, according to a study published online June 17 in JAMA Network Open.
Elizabeth C. Oelsner, M.D., from the Columbia University Irving Medical Center in New York City, and colleagues used data from 14 ongoing National Institutes of Health-funded cohorts to assess time to recovery following severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and identify factors associated with recovery by 90 days. The analysis included 4,708 participants.
The researchers found that 22.5 percent of participants did not recover by 90 days postinfection, with a median time to recovery of 20 days. There were significant differences in restricted mean recovery time by 90 days postinfection, according to sociodemographic, clinical, and lifestyle characteristics, particularly by acute infection severity (outpatient versus critical hospitalization: 32.9 versus 57.6 days). Vaccination prior to infection (hazard ratio [HR], 1.30) and infection during the sixth wave (Omicron variant) versus the first wave (HR, 1.25) were associated with recovery by 90 days postinfection. Reduced severity of acute infection mediated these associations (33.4 and 17.6 percent, respectively). There was an unfavorable association between recovery and female sex (HR, 0.85) and prepandemic clinical cardiovascular disease (HR, 0.84). Similar results were seen for reinfections.
"These findings suggest that interventions to reduce severity of acute infection, such as vaccination, may help to mitigate the increased risk of persistent symptoms observed in women and adults with suboptimal prepandemic health," the authors write.
Two authors disclosed ties to the pharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted June 2024
Further Support and Information on COVID-19
Read this next
Persistent, New Mucus Plugs Associated With Faster Decline in FEV1 in COPD
WEDNESDAY, May 21, 2025 -- For patients with chronic obstructive pulmonary disease (COPD), persistent and newly formed mucus plugs are associated with a faster decrease in forced...
Combinations of Chronic, Physical Illnesses Up the Risk of Subsequent Depression
WEDNESDAY, May 21, 2025 -- Certain groups of physical multimorbidity may be associated with a higher risk of subsequent depression, according to a study published online May 13...
Adding Team Therapist Reduces Burnout for Critical Care Nurses
TUESDAY, May 20, 2025 -- For nurses in critical care areas, adding a team therapist can reduce burnout and improve resilience, according to a study presented at the American...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.