Maternal Distress Tied to Changes in Brain Growth of Offspring
By Lori Solomon HealthDay Reporter
FRIDAY, June 21, 2024 -- Regional neonatal brain volumes are associated with elevated maternal psychological distress, according to a study published online June 20 in JAMA Network Open.
Susan Weiner, from Children’s National Hospital in Washington, D.C., and colleagues examined the association between the pandemic and rising maternal psychological distress with brain growth in newborns using quantitative three-dimensional volumetric magnetic resonance imaging (MRI). The analysis included 56 mother-infant dyads recruited during the pandemic and an existing, prepandemic normative healthy cohort (103 dyads).
The researchers found that scores on anxiety and stress measures were significantly increased in the pandemic cohort, and infants of mothers with elevated maternal distress showed median volume reductions in white matter (−0.36 cm3), right hippocampal (−0.35 cm3), and the left amygdala (−0.49 cm3) versus infants of mothers with low distress levels. Elevated trait anxiety remained significantly associated with decreased left amygdalar volumes (−0.71) when adjusting for the cohort effect of the pandemic.
"These findings suggest that increased maternal mental health symptoms during the COVID-19 pandemic are associated with subsequent changes in regional brain growth in newborn offspring," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted June 2024
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