Diet, Exercise Intervention May Aid Chemotherapy Outcomes in Breast Cancer
Medically reviewed by Drugs.com.
By Lori Solomon HealthDay Reporter
FRIDAY, Sept. 15, 2023 -- A home-based diet and exercise intervention could improve outcomes for women undergoing chemotherapy for breast cancer, according to a study published online Sept. 1 in the Journal of Clinical Oncology.
Tara Sanft, M.D., from Yale University in New Haven, Connecticut, and colleagues randomly assigned 173 women with stage I to III breast cancer to usual care (86 patients) or a home-based exercise and nutrition intervention with counseling sessions delivered by oncology-certified registered dietitians (87 patients).
The researchers found that participants in the intervention group had significantly greater improvements in exercise and diet quality compared with the usual care group. The proportion of patients who achieved ≥85 percent relative dose intensity was similar between the groups, as was the proportion of patients who had at least one dose reduction and/or delay. Among 72 women who received neoadjuvant chemotherapy, those in the intervention group were significantly more likely to have a pathologic complete response versus women in the usual care group (53 versus 28 percent).
"Further explanation is needed since it wasn't the primary outcome of our study, but there's an exciting possibility that diet and exercise can influence chemotherapy outcomes through factors other than just how much of chemotherapy was completed," senior author Melinda Irwin, Ph.D., also from Yale University, said in a statement.
Several authors disclosed ties to the pharmaceutical industry.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2023
Read this next
Donepezil Not Beneficial for Cognitive Impairment in Breast Cancer Survivors
FRIDAY, May 24, 2024 -- A once-daily dose of donepezil does not improve cognitive function among breast cancer survivors exposed to chemotherapy one to five years earlier...
ASCO: Survivors of Early Breast Cancer Can Successfully Attempt Pregnancy
THURSDAY, May 23, 2024 -- Most survivors of stage 0 to III breast cancer who attempt pregnancy postdiagnosis are able to become pregnant and have a live birth, according to a...
4-Dimensional Model Can Predict Lymph Node Metastases in Breast Cancer
THURSDAY, May 23, 2024 -- A deep learning model using tumor dynamic contrast-enhanced breast magnetic resonance imaging (MRI) has high sensitivity for identifying lymph node...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.