Skip to main content

Deaths Due to Opioid Toxicity Up in U.S. During COVID-19

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

TUESDAY, July 11, 2023 -- Deaths due to opioid toxicity increased during the COVID-19 pandemic, according to a study published online July 7 in JAMA Network Open.

Tara Gomes, Ph.D., from St. Michael's Hospital in Toronto, and colleagues characterized the societal burden of unintended opioid-related deaths in the United States. The proportion of all deaths that were attributable to unintentional opioid toxicity were examined by year and age group. In addition, the total years of life lost (YLL) due to unintentional opioid toxicity was estimated, overall, and by sex and age group.

Data were included for 422,605 unintentional deaths due to opioid toxicity between 2011 and 2021. The researchers found that there was a 289 percent increase in the number of unintentional deaths due to opioid toxicity, from 19,395 to 75,477. From 2011 to 2021, the percentage of all deaths that were attributed to opioid toxicity increased from 1.8 to 4.5 percent. By 2021, opioid toxicity was responsible for 10.2, 21.7, and 21.0 percent of deaths among those aged 15 to 19, 20 to 29, and 30 to 39 years, respectively. Over the study period, the YLL due to opioid toxicity increased 276 percent. YLL plateaued between 2017 and 2019 (7.0 and 7.2 YLL per 1,000) but then increased by 62.9 percent between 2019 and 2021, reaching 11.7 YLL per 1,000.

"The crisis of deaths due to opioid toxicity across the U.S. worsened substantially during the COVID-19 pandemic, with one in 22 deaths in 2021 attributable to unintentional opioid toxicity," the authors write

One author disclosed past employment with Sanofi Pasteur.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Read this next

Residual Risk Seen for Death, Postacute Sequelae in Third Year After COVID-19 Hospitalization

THURSDAY, June 13, 2024 -- For individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the risks for death and postacute sequelae of COVID-19...

Systemic Side Effects of COVID-19 Vaccine Tied to Greater nAB Response

TUESDAY, June 11, 2024 -- Short-term systemic side effects of the severe acute respiratory coronavirus 2 (SARS-CoV-2) mRNA vaccine are associated with greater long-lasting...

Nirmatrelvir-Ritonavir No Aid for Long COVID Symptoms

MONDAY, June 10, 2024 -- A 15-day course of nirmatrelvir-ritonavir (NMV/r) is safe but does not demonstrate a significant benefit for improving postacute sequelae of SARS-CoV-2...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.