Zevaskyn
Generic name: prademagene zamikeracel topical [ pra-DEM-a-jeen-ZAM-i-KER-a-sel ]
Drug class: Miscellaneous topical agents
What is Zevaskyn?
Zevaskyn (for the skin) is used adults and children to treat wounds caused by a certain type of dystrophic epidermolysis bullosa.
Your doctor will make sure you can be treated with Zevaskyn.
Zevaskyn may also be used for purposes not listed in this medication guide.
Zevaskyn side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Zevaskyn may cause serious side effects. Call your doctor at once if you have:
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signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite; or
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increased pain, swelling, oozing, or skin changes around the treatment site.
Common side effects of Zevaskyn may include:
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procedure pain; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Related/similar drugs
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
This treatment should not be used if you have a certain gene type. Ask your doctor if you have any questions.
Tell your doctor if you have or have ever had:
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an active or recent infection; or
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use other medications.
Using Zevaskyn may increase your risk of developing cancer. Ask your doctor about your individual risk and what symptoms to watch for.
Zevaskyn is made using human and cattle products. They may contain viruses or other infectious agents. The products are tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
It is not known if Zevaskyn will harm an unborn baby. Use birth control during treatment with Zevaskyn and tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
How is Zevaskyn given?
Zevaskyn is applied in a medical setting by specially trained healthcare professionals.
Before treatment, your doctor will take a sample of your skin that is sent to a laboratory where the skin cells will be used to make Zevaskyn.
You will not receive the medicine on the same day your skin cell sample is taken. It will take time to process your skin cells and your doctor will determine your treatment schedule.
A second skin sample collection attempt may be needed to make Zevaskyn and your treatment plan may be delayed or changed.
It may not be possible to apply the medicine to all wounds with each treatment.
Make sure to follow up with your doctor about caring for dressings on treated wounds. Keep dressings dry and leave the treatment area alone for 5-10 days to allow for healing.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment to receive Zevaskyn.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid while receiving Zevaskyn?
Avoid letting treated areas come in contact with water until gauze backing falls off (usually within 2 to 3 weeks after application).
What other drugs will affect Zevaskyn?
Tell your doctor about all your other medicines, especially:
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antibiotic such as vancomycin or amikacin.
Other drugs may affect Zevaskyn, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Zevaskyn Biosimilars
Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.
Reference products
These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for Zevaskyn.
zevaskyn (Prademagene zamikeracel) - Abeona Therapeutics Inc.
| Formulation type | Strength |
|---|---|
| Tray & Lid | 41.25 CM^2 |
More about Zevaskyn (prademagene zamikeracel topical)
- Compare alternatives
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: miscellaneous topical agents
- En español
Professional resources
Related treatment guides
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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