Calfactant
Generic name: calfactant [ kal-FAK-tant ]
Brand name: Infasurf
Dosage form: intratracheal suspension (35.7 mg/mL)
Drug class: Lung surfactants
What is calfactant?
Calfactant is a lung surface acting agent, or "surfactant." It helps the lungs function normally. Calfactant is similar to the natural fluid in the lungs that helps maintain effective breathing.
Calfactant is used to treat or prevent respiratory distress syndrome (RDS) in a premature baby whose lungs have not fully developed.
Calfactant may also be used for other purposes not listed in this medication guide.
Calfactant side effects
Calfactant causes few side effects. There is a possibility that the baby will have breathing difficulties during the calfactant treatment, and these problems may require further treatment by health care professionals. Your baby will remain under constant supervision during treatment with calfactant.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Warnings
Your baby will receive this medication in a neonatal intensive care unit (NICU) or similar hospital setting.
Calfactant is given directly into the baby's lungs through a breathing tube that is also connected to a ventilator (a machine that moves air in and out of the lungs to help your baby breathe easier and get enough oxygen).
Your baby will remain under constant supervision during treatment with calfactant.
Before taking this medicine
To best participate in the care of your baby while he or she is in the NICU, carefully follow all instructions provided by your baby's caregivers.
How is calfactant given?
Calfactant is given directly into the baby's lungs through a breathing tube. Your baby will receive this medication in a neonatal intensive care unit (NICU) or similar hospital setting.
The breathing tube is connected to a ventilator (a machine that moves air in and out of the lungs to help your baby breathe easier and get enough oxygen).
Calfactant is given as soon as possible after the baby's birth, usually within 30 minutes.
Calfactant is usually given every 12 hours for up to 3 doses.
Your baby's breathing, blood pressure, oxygen levels, and other vital signs will be watched closely during treatment with calfactant.
What happens if a dose is missed?
Since calfactant is given as needed by a healthcare professional, it is not likely that your baby will miss a dose.
What happens if an overdose is given?
Since calfactant is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. However, an overdose of calfactant is not expected to produce life-threatening symptoms.
What should be avoided after receiving calfactant?
Follow your doctor's instructions about any restrictions in feeding, medications, or activity after your baby has been treated with calfactant.
What other drugs will affect calfactant?
Your baby's caregivers will manage and monitor all medications given to your baby during treatment in the NICU. A drug interaction between calfactant and other medications is not expected to occur.
Do not give any medications to your baby that have not been prescribed by the baby's doctor. This includes vitamins, minerals, or herbal products.
Calfactant Biosimilars
Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.
Reference products
These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for calfactant.
Infasurf (calfactant) - ONY Biotech Inc.
| Formulation type | Strength |
|---|---|
| Single-Dose Vial | 105 mg/3 mL (35 mg/mL) |
| Single-Dose Vial | 210 mg/6 mL (35 mg/mL) |
View Infasurf information in detail.
More about calfactant
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: lung surfactants
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Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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