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How is Sandostatin given/administered?

Medically reviewed by Sally Chao, MD. Last updated on Sep 27, 2023.

Official answer


The immediate-release form of Sandostatin (octreotide acetate) is administered using a needle injected under your skin (subcutaneously) or into a vein (intravenously). Most often, the injection is given subcutaneously.

Patients are usually able to inject this short-acting drug on themselves without going to a doctor’s office or clinic. Friends, caregivers or family members may also be able to administer the shot.

The medicine is stored in vials, ampules or dosing pens. Your doctor will tell you how much medication to inject, how often to inject it and where. Typically, injections are given around the hip, thigh or abdominal area. The site of injection should be rotated according to your doctor’s instructions. Most patients will need 2 to 4 daily injections at set times throughout the day.

Before using Sandostatin, make sure that the medication is not expired and the solution is clear, colorless and free of any particles.

Detailed instructions for delivering the injection will come with the medication or be provided by your doctor. Read the instructions carefully. If you find any of the steps confusing, ask your doctor to clarify. Before administering the injection at home, make sure that a trained medical professional has shown you, or the person expected to perform the shot, how to do it properly.

Long-acting octreotide acetate, or Sandostatin LAR Depot, is injected into the gluteus (buttocks) muscle and must be performed by a health care provider. These injections are usually given in 4-week intervals.

  1. U.S. National Library of Medicine MedlinePlus. Octreotide injection. May 15, 2020. Available at: [Accessed September 20, 2021].
  2. U.S. Food and Drug Administration (FDA). Sandostatin®. 2002. Available at: [Accessed September 20, 2021].

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