Tacrolimus (International)

In the US, Tacrolimus (tacrolimus systemic) is a member of the drug class calcineurin inhibitors and is used to treat Crohn's Disease, Graft-versus-host disease, Nephrotic Syndrome, Organ Transplant - Rejection Prophylaxis and Organ Transplant - Rejection Reversal.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

D11AH01,L04AA05,L04AD02

CAS registry number (Chemical Abstracts Service)

0104987-11-3

Chemical Formula

C44-H69-N-O12

Molecular Weight

804

Therapeutic Category

Immunosuppressant

Chemical Name

Immunosuppreβant derived from Streptomyces tsukubaensis

Foreign Names

Tacrolimusum (Latin)
Tacrolimus (German)
Tacrolimus (French)
Tacrolimus (Spanish)

Generic Names

Tacrolimus (OS: USAN, BAN)
Tacrolimus (PH: USP 41)
Tacrolimus Hydrate (OS: JAN)
FK 506 (Fujisawa) (IS)
FR 900506 (IS)
L 683590 (IS)
Tacrolimus Hydrate (PH: JP XVII)
Tacrolimus Monohydrate (PH: BP 2018, Ph. Eur. 9.3)

Brand Names

Adoport
Lek, Slovenia
Adoport 0,5 mg
Sandoz, Turkey
Adoport 1 mg
Sandoz, Turkey
Adoport 5 mg
Sandoz, Turkey
Advagraf
Astellas, Bosnia & Herzegowina; Astellas, Canada; Astellas, Estonia; Astellas, Georgia; Astellas, Hong Kong; Astellas, Croatia (Hrvatska); Astellas, Iceland; Astellas, Italy; Astellas, Latvia; Astellas, Norway; Astellas, Philippines; Astellas, Portugal; Astellas, Romania; Astellas, Russian Federation; Astellas, Slovakia; Astellas, Taiwan; Astellas, South Africa; Astellas Pharma, Poland; Astellas Pharma, Serbia; Astellas Pharma China, China; Astellas Pharma Europe, Netherlands; Astellas Pharma Europe BV, Greece; DKSH, Malaysia
Advagraf 0,5 mg
Astellas, Turkey
Advagraf 0,5 mg retard
Astellas, Hungary
Advagraf 0.5mg
Astellas, Switzerland
Advagraf 1 mg
Astellas, Turkey
Advagraf 1 mg retard
Astellas, Hungary
Advagraf 1mg
Astellas, Switzerland
Advagraf 3 mg retard
Astellas, Hungary
Advagraf 3mg
Astellas, Switzerland
Advagraf 5 mg
Astellas, Turkey
Advagraf 5 mg retard
Astellas, Hungary; Astellas Pharma, Germany
Advagraf 5mg
Astellas, Switzerland
Advagraf LP
Hikma, Tunisia
Advagraf PR
Astellas Pharma, Cyprus
Advagraf Prolonged Release
Astellas, Slovenia
Advagraf XL
Astellas Pharma, Australia
Astagraf XL
Astellas, United States
Atolimus
Beximco, Bangladesh
Cellmune 0.1%
Industrial Farmaceutica Cantabria, United Kingdom
Cidimus
Novartis, Chile; Sandoz, Poland
Cromus
Procaps, Colombia
Cromus Ung
Unimed, Peru
Dermitopic 0.1%
Pharmaswiss Ceska Republika, United Kingdom
Effac
Meider, Taiwan
Envarsus
Chiesi, Greece; Chiesi, Lithuania; Chiesi Farmaceutici, Slovenia; Chiesi Pharmaceuticals, Bosnia & Herzegowina; Chiesi Pharmaceuticals, Poland; Providens, Croatia (Hrvatska)
Envarsus 0.75 mg retard
Chiesi, Hungary
Envarsus 1 mg retard
Chiesi, Hungary
Envarsus LP
Chiesi, France
Envarsus XR
Veloxis Pharmaceuticals, United States
Gecrol
Heaton, Czech Republic; Heaton, Slovakia
Imugraft 0.5
Ambica, Philippines
Lecron
PharOS, Italy
Limus
Alco, Bangladesh
Modigraf
Astellas, Lithuania; Astellas, Slovenia; Astellas, Slovakia; Astellas Pharma, Germany; Astellas Pharma, Denmark; Astellas Pharma Europe, Iceland; Orifarm, Norway
Modigraf 0.2 mg
Astellas, Switzerland; Astellas, Hungary
Modigraf 1 mg
Astellas, Hungary
Modigraf 1mg
Astellas, Switzerland
Mustopic
Systopic, India
Norgraf
Nordic, Peru
Oligma
Eczacibasi Ilac Pazarlama, Turkey
Pacrolim
Alphapharm, Australia
Panolimus
Biem, Turkey
Proalid
Italmex, Mexico
Prodermic
Iqfarma, Peru
Produke
Titan, Georgia
Produke SR
Titan, Georgia
Prograf
Astellas, Bosnia & Herzegowina; Astellas, Canada; Astellas, Czech Republic; Astellas, Egypt; Astellas, Georgia; Astellas, Greece; Astellas, Hong Kong; Astellas, Indonesia; Astellas, Israel; Astellas, Italy; Astellas, South Korea; Astellas, Macedonia; Astellas, Malta; Astellas, Philippines; Astellas, Portugal; Astellas, Sweden; Astellas, Slovakia; Astellas, Thailand; Astellas, Turkey; Astellas, Taiwan; Astellas, United States; Astellas, South Africa; Astellas Pahrmaceuticals Aebe, Cyprus; Astellas Pharma, Australia; Astellas Pharma, Denmark; Astellas Pharma, United Kingdom; Astellas Pharma, Poland; Astellas Pharma, Singapore; Astellas Pharma a/s, Iceland; Astellas Pharma China, China; Astellas Pharma Europe, Romania; Astellas Pharma Singapore, Vietnam; DKSH, Malaysia; Farmagon, Norway; Gador, Argentina; Gador, Chile; Gador, Paraguay; Hikma, Kuwait; Hikma, Lebanon; Hikma, Oman; Hikma, Tunisia; Janssen, Venezuela; Janssen-Cilag, Brazil; Orifarm, Norway
Prograf 0.5 mg
Astellas, Hungary
Prograf 0.5mg
Astellas, Switzerland; Astellas, Israel; Gador, Uruguay
Prograf 1 mg
Astellas, Hungary
Prograf 1mg
APS, Switzerland; Astellas, Switzerland; Astellas, Israel
Prograf 5 mg
Astellas, Hungary
Prograf 5 mg/ml
Astellas, Hungary
Prograf 5mg
Astellas, Switzerland; Astellas, Israel; Gador, Uruguay
Prograf 5mg/ml
Astellas, Switzerland; Astellas Pharma, Austria; Astellas Pharma, Germany
Prograf XL
Astellas Pharma, Australia; Gador, Argentina; Gador, Chile
Protopic
Astellas, Georgia; Astellas, Greece; Astellas, Hong Kong; Astellas, Italy; Astellas, Portugal; Astellas, Taiwan; Astellas Ireland, Serbia; Astellas Pharma China, China; Janssen, Malaysia; Janssen, Philippines; Janssen, Singapore; Janssen-Cilag/Astellas, Indonesia; LEO, Norway; LEO Pharma, Canada; LEO Pharma, Greece; LEO Pharma, Lithuania; LEO Pharma, Latvia; LEO Pharma, Turkey; LEO Pharma, United States; Leofarma, Brazil; Roche Uruguay, Uruguay
Protopic 0.01%
Astellas, Croatia (Hrvatska)
Protopic 0.03%
Astellas, Switzerland; Astellas, Croatia (Hrvatska); Astellas, Israel; Astellas Pharma, Cyprus; Astellas Pharma, Poland; LEO Pharma, Spain; LEO Pharma, Netherlands
Protopic 0.1%
Astellas, Israel; Astellas Pharma, Cyprus; LEO Pharma, Switzerland; LEO Pharma, Netherlands; Leo Pharma A/S, Iceland
Protopy
Astellas, Lithuania
Regraf
MMC, Georgia
Remus
Square, Bangladesh
Rocimus
Mega Lifesciences, Philippines
Seegraf
Micro Labs, India
Tacloran
Wockhardt, India
Tacni
Pliva, Bosnia & Herzegowina; Pliva, Croatia (Hrvatska); Teva, Czech Republic; Teva, Spain; Teva, Greece; Teva, Lithuania; Teva, Norway; Teva Pharma, Cyprus; Teva Pharma, Slovenia; Teva Pharmaceuticals, Poland
Tacni 0.5mg
ratiopharm Arzneimittel, Austria; Teva, Germany; Teva, Hungary; Teva, Luxembourg; Teva Pharma, Switzerland
Tacni 1mg
ratiopharm Arzneimittel, Austria; Teva, Germany; Teva, Hungary; Teva, Luxembourg; Teva Pharma, Switzerland
Tacni 5mg
ratiopharm Arzneimittel, Austria; Teva, Germany; Teva, Hungary; Teva, Luxembourg; Teva Pharma, Switzerland
Tacpan 0,5mg
Panacea Biotec Germany, Germany
Tacpan 1mg
Panacea Biotec Germany, Germany
Tacpan 5mg
Panacea Biotec Germany, Germany
Tacroderm
AHPL, India
Tacrograf
Biocon, India
Tacrol
Acme, Bangladesh
Tacroli
Hwang's, Taiwan
Tacrolim
Incepta, Bangladesh
Tacrolimus
Accord Healthcare, United States; Belcher Pharmaceuticals, United States; Dr. Reddy's, United States; Fougera, United States; Hospira, United States; Lek, Bosnia & Herzegowina; Mylan, United States; Panacea Biotec, United States; Sandoz, United States; Strides Pharma, United States
Tacrolimus Accord
Accord, Lithuania; Accord Healthcare, Poland
Tacrolimus Accord 0.1%
Accord Healthcare, United Kingdom
Tacrolimus Accord Healthcare
Accord Healthcare, Italy
Tacrolimus Cinfa
Cinfa, Spain
Tacrolimus Medis
Medis, Tunisia
Tacrolimus Mylan
Mylan, Spain
Tacrolimus Pharma Arte
Pharma Arte, Paraguay
Tacrolimus PharmaSwiss
PharmaSwiss, Estonia; PharmaSwiss, Lithuania
Tacrolimus Pierre Fabre 0.1%
Pierre Fabre, United Kingdom
Tacrolimus Sandoz
Novartis, New Zealand; Sandoz, Hong Kong
Tacrolimus Servimedic
Servimedic, Uruguay
Tacrolimus Stada
STADA, Spain
Tacrolimus Teva 0.1%
Teva Pharmaceuticals, United Kingdom
Tacrolin
Farma-Tek, Turkey
Tacromus
Zydus Cadila, India
Tacrotec
Marzan Pharma, Philippines
Tacrotopic
Lafedar, Argentina
Tacroz
Glenmark, Ecuador; Glenmark, India; Glenmark Pharmaceuticals, Vietnam
Tacroz Forte
Glenmark, Ecuador; Glenmark, India; Glenmark, Peru; Glenmark Pharmaceuticals, Vietnam
Tagraf
Panacea Biotech, Philippines
Takrocept
Intas, Poland
Takrolimus Belupo
Belupo, Croatia (Hrvatska)
Takrolimus Genera
Genera, Croatia (Hrvatska)
Takrolimus Sandoz
Lek, Serbia
Taliximun
PharmaSwiss, Poland
Tames
Olcare Laboratories, India
Tarfic
Libbs, Brazil
Tarolimus 0.03%
Andalous, Egypt
Tartrime
Gobbi-Novag, Argentina; Juste, Spain
T-Inmun
Complex Therapeutics, Chile; Mediderm, Chile; Recalcine, Ecuador; Recalcine, Paraguay
Topgraf
GlaxoSmithKline, India
Topiclin
Solebio, Turkey
Tracsus
Alvogen, Croatia (Hrvatska); Alvogen Luxembourg, Romania; Cinfa, Macedonia; Laboratorios Cinfa, Bosnia & Herzegowina
Traderma
Serral, Mexico
T-Top
Wallace, India
T-Top Forte
Wallace, India
Vingraf
Emcure Pharma, Philippines
Adoport
Sandoz, Belgium; Sandoz, Portugal; Sandoz España, Spain
Adoport 0,5 mg
Sandoz, France; Sandoz, United Kingdom
Adoport 0.75 mg
Sandoz, United Kingdom
Adoport 1 mg
Sandoz, France; Sandoz, United Kingdom
Adoport 2 mg
Sandoz, France; Sandoz, United Kingdom
Adoport 5 mg
Sandoz, France; Sandoz, United Kingdom
Adport
Sandoz, Denmark; Sandoz, Georgia; Sandoz, Netherlands; Sandoz, Sweden
Adport 0,5 mg
Sandoz, Austria
Adport 1 mg
Sandoz, Austria
Adport 2 mg
Sandoz, Austria
Adport 5 mg
Sandoz, Austria
Advagraf
Astellas, Czech Republic; Astellas, Spain; Astellas, Finland; Astellas, Ireland; Astellas, South Korea; Astellas, Lithuania; Astellas, Sweden; Astellas, Thailand; Astellas Pharma, Belgium; Astellas Pharma, Denmark; Astellas Pharma, Singapore; Astellas Pharma Singapore, Vietnam
Advagraf 0,5 mg
Astellas, France
Advagraf 0,5 mg retard
Abacus, Austria; Astellas Pharma, Germany; Astellas Pharma Europe, Austria; Haemato Pharm, Austria
Advagraf 0.5mg
Astellas, Israel
Advagraf 0.5mg prolonged-release
Astellas Pharma, United Kingdom
Advagraf 1 mg
Astellas, France
Advagraf 1 mg prolonged-release
Astellas Pharma, United Kingdom
Advagraf 1 mg retard
Astellas Pharma, Germany; Astellas Pharma Europe, Austria
Advagraf 3 mg prolonged-release
Astellas Pharma, United Kingdom
Advagraf 3 mg retard
Astellas Pharma, Germany
Advagraf 3mg
Astellas, France
Advagraf 5 mg
Astellas, France
Advagraf 5 mg prolonged-release
Astellas Pharma, United Kingdom
Advagraf 5 mg retard
Abacus, Austria; Astellas Pharma Europe, Austria; Emra-Med Arzneimittel, Austria
Advagraf-0.5
Astellas, Luxembourg
Advagraf-1
Astellas, Luxembourg
Advagraf-3
Astellas, Luxembourg
Advagraf-5
Astellas, Luxembourg
Crilomus
Hexal, Germany
Crilomus 0.5mg
Sandoz, Switzerland
Crilomus 0.75mg
Sandoz, Switzerland
Crilomus 1mg
Sandoz, Switzerland
Crilomus 2mg
Sandoz, Switzerland
Crilomus 5mg
Sandoz, Switzerland
Dermitopic 0.1%
PharmaSwiss, Poland
Envarsus
Chiesi, Czech Republic; Chiesi, Germany; Chiesi, Denmark; Chiesi, Estonia; Chiesi, Spain; Chiesi, United Kingdom; Chiesi, Ireland; Chiesi, Norway; Chiesi, Sweden; Chiesi Farmaceutici, Netherlands; Chiesi Pharma, Finland
Envarsus 0.75mg
Chiesi, Switzerland; Chiesi Farmaceutici, Austria
Envarsus 1mg
Chiesi, Switzerland; Chiesi Farmaceutici, Austria
Envarsus 4mg
Chiesi, Switzerland; Chiesi Farmaceutici, Austria
Framebin
Pisa, Mexico
Graceptor
Astellas, Japan
Limustin
Landsteiner, Mexico
Modigraf
Astellas, Czech Republic; Astellas, Estonia; Astellas, Spain; Astellas, Finland; Astellas, France; Astellas, Ireland; Astellas, Latvia; Astellas, Norway; Astellas, Sweden; Astellas Pharma, United Kingdom; Astellas Pharma, Poland; Astellas Pharma Europe, Netherlands
Modigraf 0,2mg
Astellas Pharma Europe, Austria
Modigraf 1mg
Astellas Pharma Europe, Austria
Octralin
Raam, Mexico
Pharmacor Tacrolimus
Pharmacor, Australia
Prograf
Astellas, Bulgaria; Astellas, Spain; Astellas, Finland; Astellas, France; Astellas, Croatia (Hrvatska); Astellas, Ireland; Astellas, Japan; Astellas, South Korea; Astellas, Malta; Astellas, Norway; Astellas, Sweden; Astellas Ireland, Serbia; Astellas Pharma, United Kingdom; Janssen-Cilag, Mexico
Prograf 0,5mg
Astellas Pharma, Austria; Astellas Pharma, Germany
Prograf 1mg
Astellas Pharma, Austria; Astellas Pharma, Germany
Prograf 5mg
Astellas Pharma, Austria; Astellas Pharma, Germany
Prograf XL
Janssen-Cilag, Mexico
Prograft
Astellas, Belgium; Astellas Pharma Europe, Netherlands; BModesto, Netherlands; Delphi, Netherlands; Dr. Fisher Farma, Netherlands; EU-Pharma, Netherlands; Euro Registratie, Netherlands; Medcor Pharmaceuticals, Netherlands
Prograft-0.5
Astellas, Luxembourg
Prograft-1
Astellas, Luxembourg
Prograft-5
Astellas, Luxembourg
Protopic
Astellas, South Korea; Astellas, South Africa; Hikma, Oman; Janssen, Thailand; LEO, Ireland; LEO Pharma, Czech Republic; LEO Pharma, Denmark; LEO Pharma, Estonia; LEO Pharma, Finland; LEO Pharma, Sweden; Productos Roche, Chile; Roche, Ecuador; Roche, Mexico
Protopic 0.03%
Astellas, Japan; Astellas, Slovakia; Eurim-Pharm, Austria; LEO, Germany; LEO Laboratories, United Kingdom; Leo Pharma, Austria; Leo Pharma, Belgium; Leo Pharma, Finland; Leo Pharma, France; Leo Pharma, Hungary; Leo Pharma, Luxembourg; Leo Pharma, Romania
Protopic 0.1%
Astellas, Japan; Astellas, Slovakia; Astellas Pharma, Poland; Eurim-Pharm, Austria; LEO, Germany; LEO Laboratories, United Kingdom; Leo Pharma, Austria; Leo Pharma, France; Leo Pharma, Hungary; Leo Pharma, Luxembourg; Leo Pharma, Romania
Sandoz Tacrolimus
Sandoz, Canada
Tacforius
Teva Nederland, Netherlands
Tacni
Pharmachemie, Netherlands; Teva, Sweden
Tacrobell
Chong Kun Dang, South Korea
Tacrocel
Sandoz, Croatia (Hrvatska)
Tacrocel 0.5mg
LEK Pharmaceuticals, Israel
Tacrocel 1mg
LEK Pharmaceuticals, Israel
Tacrocel 5mg
LEK Pharmaceuticals, Israel
Tacrocin
Intas, Philippines
Tacroderm
Lazar, Argentina
Tacrolimus
Ayumi Pharmaceutical, Japan; Mylan Seiyaku, Japan; Nichi-Iko Pharmaceutical, Japan; Nihon Generic, Japan; Nipro, Japan; Sandoz, Argentina; Sandoz, Georgia; Towa Yakuhin, Japan; Nipro Pharma Nipurofama, Japan
Tacrolimus 0.1%
Iwaki Seiyaku, Japan; Pola Pharma, Japan; Takata Pharmaceutical, Japan; Nipro Pharma Nipurofama, Japan
Tacrolimus Accord
Accord Healthcare, Netherlands; Lyomark Pharma, Germany
Tacrolimus AL
Aliud Pharma, Germany
Tacrolimus Apotex
Pharmacor, Australia
Tacrolimus CF
Centrafarm, Netherlands
Tacrolimus Heumann
Heumann, Germany
Tacrolimus HEXAL
Hexal, Germany
Tacrolimus Lek
LEK farmacevtska, Macedonia
Tacrolimus Pergamus
Accord Healthcare, Bulgaria; Actavis, Bulgaria
Tacrolimus Sandoz
Sandoz, Australia; Sandoz, Netherlands; Sandoz, Romania; STADA, Spain
Takrozem
Pierre Fabre, Netherlands
Talymus 0.1%
Senju Seiyaku, Japan
Tarimus
Hanmi, South Korea

Glossary

Term	Definition
BAN	British Approved Name
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The Drugs.com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

International Drug Name Search