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Sitaxentan

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C02KX03

CAS registry number (Chemical Abstracts Service)

0184036-34-8

Chemical Formula

C18-H15-Cl-N2-O6-S2

Molecular Weight

454

Therapeutic Categories

Treatment of pulmonary hypertension

Endothelin receptor antagonist

Chemical Names

N-(4-Chlor-3-metylisoxazol-5-yl)-2-[(4,5-metylendioxy-2-metylphenyl)acetyl]tiophen-3-sulfonamid (IUPAC)

N-(4-Chlor-3-metylisoxazol-5-yl)-2-[2-(6-metyl-1,3-benzodioxol-5-yl)acetyl]tiophen-3-sulfonamid

N-(4-Chloro-3-metyl-5-isoxazolyl)-2-[[4,5-(metylenedioxy)-o-tolyl]acetyl]-3-tiophenesulfonamide (WHO)

3-tiophenesulfonamide, N-(4-chloro-3-metyl-5-isoxazolyl)-2-[[6-metyl-1,3-benzodioxol-5-yl]acetyl]-

Foreign Names

  • Sitaxentanum (Latin)
  • Sitaxentan (German)
  • Sitaxentan (French)
  • Sitaxentan (Spanish)

Generic Names

  • Sitaxentan (OS: USAN)
  • IPI 1040 (IS)
  • Sitaxsentan (IS)
  • Sitaxentan Sodium (OS: USAN)
  • LGLS (IS)
  • TBC-11241 (IS)
  • TBC-11251 (IS: TexasBiotechn)
  • TBC-2576 (IS)
  • TBC-3214 (IS)

Brand Names

  • Thelin
    Pfizer, Greece; Pfizer Consumer Healthcare, Ireland

Glossary

TermDefinition
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Further information

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