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Isotretinoin

In the US, Isotretinoin (isotretinoin systemic) is a member of the following drug classes: miscellaneous antineoplastics, miscellaneous uncategorized agents and is used to treat Acne, Acute Nonlymphocytic Leukemia, Granuloma Annulare, Melanoma - Metastatic, Pityriasis rubra pilaris and Rosacea.

US matches:

UK matches:

  • ISOTRETINOIN 0.05% GEL (Leaflet)

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

D10AD04,D10BA01

CAS registry number (Chemical Abstracts Service)

0004759-48-2

Chemical Formula

C20-H28-O2

Molecular Weight

300

Therapeutic Categories

Antiacne agent

Retinoid

Chemical Name

Retinoic acid, 13-cis-

Foreign Names

  • Isotretinoinum (Latin)
  • Isotretinoin (German)
  • Isotrétinoïne (French)
  • Isotretinoina (Spanish)

Generic Names

  • Isotretinoin (OS: USAN, BAN)
  • Isotretinoina (OS: DCIT)
  • Isotrétinoïne (OS: DCF)
  • 13-cis-retinoic acid (IS)
  • Ro 4-3780 (IS)
  • Isotretinoin (PH: BP 2018, Ph. Eur. 9.5, USP 41)
  • Isotrétinoïne (PH: Ph. Eur. 9)
  • Isotretinoinum (PH: Ph. Eur. 9.5)

Brand Names

  • Aaiso
    Iscon Life Sciences, India
  • Absorica
    Ranbaxy, United States
  • Accuran
    Nexus Medicals, Greece
  • Accure
    Dermagen, Pakistan
  • Accutane Roche
    Hoffmann-La Roche, Canada
  • Accutin
    Sandoz, Denmark
  • Acne Free
    Amoun, Egypt
  • Acne Free 0.025%
    Amoun, Egypt
  • Acne Free 0.05%
    Amoun, Egypt
  • Acnecur
    Catedral, Paraguay
  • Acnecutan
    Jadran Galenski, Russian Federation
  • Acnegen 10 mg
    Biogen, Turkey
  • Acnegen 20 mg
    Biogen, Turkey
  • Acnemin
    Vinas, Spain
  • Acneone
    Genesis, India
  • Acneral
    Laboratorio Chile, Chile
  • Acneral MD
    Laboratorio Chile, Chile
  • Acnestar
    Mankind, India
  • Acneta
    Taha Pharma, Tunisia
  • Acnetane
    Al Pharm, South Africa
  • Acnetin A 0.025%
    Sigma, Egypt
  • Acnetin A 0.05%
    Sigma, Egypt
  • Acnétrait 10 mg
    Arrow, France
  • Acnétrait 20 mg
    Arrow, France
  • Acnétrait 40 mg
    Arrow, France
  • Acnétrait 5 mg
    Arrow, France
  • Acnetrex 10
    Mega Lifesciences, Philippines
  • Acnetrex 20
    Mega Lifesciences, Philippines
  • Acnex-20
    Unichem, India
  • Acnezac
    Olcare Laboratories, India
  • Acnisil
    Assure Aplomb, India
  • Acnizo
    Zenon, India
  • Acno
    Ajanta, India; Paramount, Pakistan
  • Acnogen
    Genepharm, Greece
  • Acnotin
    Bago, Peru; Bagó, Ecuador; Laboratorio Bago, Chile; Mega Lifesciences, Hong Kong; Mega Lifesciences, Myanmar; Mega Lifesciences, Singapore; Mega Lifesciences, Thailand
  • Acnotren
    Pharmathen, Lebanon
  • A-Cnotren
    Pharmathen, Greece; Pharmathen, Thailand
  • Acnova
    Germed Farmaceutica, Brazil
  • Acretin 0.025%
    jamjom, Egypt
  • Acretin 0.05%
    jamjom, Egypt
  • Actaven
    Actavis Group, Poland
  • Acugen
    Olive Healthcare, Philippines
  • Acutret
    IPCA, India
  • Acutrex
    Medica Korea, Philippines
  • Adclin
    Sigman, India
  • Ai Si Jie
    Dazhong Pharmaceutical, China
  • Aisoskin
    Fidia Farmaceutici, Italy
  • Aknal
    Dong-A, South Korea
  • Aknenormin
    Almirall Hermal, Czech Republic; Almirall Hermal, Poland; Hermal, Slovakia
  • Aknenormin 10mg
    Almirall Hermal, Germany; Almirall Hermal, Hungary
  • Aknenormin 20mg
    Almirall Hermal, Germany; Almirall Hermal, Hungary
  • Aknetrent 10 mg
    Recordati, Turkey
  • Aknetrent 20 mg
    Recordati, Turkey
  • Amnesteem
    Mylan, United States
  • Apex-Isotretinoin
    Camox, South Africa
  • APO-Isotretinoin
    Apotex, Australia
  • Atlacne
    Atlas Farmc., Argentina
  • Atretin Lafrancol
    Abbott, Colombia
  • Axotret
    Axxon, Poland
  • Casius
    Swiss & North, Ecuador
  • Cecnoin
    Eurofarma, Brazil
  • Ciscutan 10 mg
    Pelpharma, Austria
  • Ciscutan 20 mg
    Pelpharma, Austria
  • Ciscutan 30 mg
    Pelpharma, Austria
  • Ciscutan 40 mg
    Pelpharma, Austria
  • Ciscutan 5 mg
    Pelpharma, Austria
  • Claravis
    Teva, United States
  • Clarus
    Mylan Pharmaceuticals, Canada
  • Contracne
    Laboratoires Bailleul, Malta
  • Contracné
    Bailleul, France
  • Cosmin
    Saffron, Pakistan
  • Curacne
    Pierre Fabre, Lebanon; Pierre Fabre, Tunisia; Pierre Fabre, Vietnam; Pierre Fabre Dermatologie, France; Pierre Fabre Dermatologie, Poland
  • Curacné
    Pierre Fabre, Czech Republic; Pierre Fabre Medicament, Slovakia
  • Curacne Gé
    Pierre Fabre, Tunisia
  • Curakne 10mg
    Pierre Fabre, Switzerland
  • Curakne 20mg
    Pierre Fabre, Switzerland
  • Curakne 40mg
    Pierre Fabre, Switzerland
  • Curakne 5mg
    Pierre Fabre, Switzerland
  • Curatane 10mg
    Douglas, Israel
  • Curatane 20mg
    Douglas, Israel
  • Curatane 5mg
    Douglas, Israel
  • Cuticilin
    Vivax, Venezuela
  • Decutan
    Actavis, Tunisia; Actavis Group, Iceland; Actavis Group, Malta
  • Dercutane
    Cantabria, Spain
  • Dermalona
    Bagó, Colombia
  • Dermatane
    Eris Pharmaceutical, Australia
  • Effederm
    c. erba, Egypt
  • Epuris
    Cipher Pharmaceuticals, Canada
  • Erynocin [+ Erythromycin]
    Sante, Pakistan
  • Esotek [+ Erythromycin]
    Zam Zam, Pakistan
  • Etrexin [+ Erythromycin]
    Vem Ilaç, Turkey
  • Eudyna 0.05%
    Abbott, Egypt
  • Faclynel
    Italmex, Mexico
  • Flexresan
    Centrum, Spain; Raymos, Argentina
  • Hyndriax
    Roemmers, Peru
  • Inerta 10 mg
    Actavis, Hungary
  • Inerta 20 mg
    Actavis, Hungary
  • Inflader
    Royal Pharma, Chile
  • I-Ret
    Adcock Ingram, India
  • Isac
    Systopic, India
  • Isdiben
    Isdin, Spain
  • Isoacne
    Pierre Fabre Iberica, Spain
  • Isoacne [+ Erythromycin]
    Neophar, Pakistan
  • Isobest
    Glenmark, India
  • Isocheck
    Pharmacheck, Peru
  • Isocural
    Pierre Fabre Sante, Belgium
  • Isocutan
    Raffo, Argentina
  • Isoderm
    Candid, Pakistan; Dermapharm, Germany; Sun-Farm, Poland
  • Isoface
    Genome, Pakistan; Interpharm, Ecuador; Procaps, Colombia; Recalcine, Paraguay; Unimed, Peru; Vivax, Venezuela
  • IsoGalen
    Galenpharma, Germany
  • Isolve
    Suiphar, Dominican Republic
  • Isoriac
    Pierre Fabre Italia, Italy
  • Isosupra
    Smb Technology, Lebanon
  • Isosupra Lidose
    Laboratoires SMB, Belgium
  • Isotane
    Micro Gratia, India; Mylan, New Zealand
  • Isotina
    Taiguk, South Korea
  • Isotinon
    Hanmi, South Korea
  • Isotrat (C2)
    Nova Química Farmacêutica, Brazil
  • Isotren
    Korean Drug, South Korea
  • Isotret-HEXAL
    Hexal, Germany
  • Isotretinoin
    Alliance Pharmaceuticals, United Kingdom; Amneal Pharmaceuticals, United States; Ennogen Healthcare, United Kingdom; Ranbaxy, United Kingdom
  • Isotretinoin Actavis
    Actavis, Sweden; Actavis, Slovakia
  • Isotretinoin AN
    Amneal Pharma, Australia
  • Isotretinoin Jenson
    Generics, Poland
  • Isotretinoin NeoFarma
    NeoFarma, Malta
  • Isotretinoin Orifarm
    Orifarm Generics, Norway; Orifarm Generics, Sweden
  • Isotretinoin Orion
    Orion Pharma, Denmark; Orion Pharma, Finland
  • Isotretinoin Ranbaxy
    Ranbaxy, Egypt
  • Isotretinoin Ratiopharm
    Ratiopharm GmbH, Iceland
  • Isotretinoin Sandoz
    Sandoz, Lithuania
  • Isotretinoin SCP
    Southern Cross Pharma, Australia
  • Isotretinoin Terapia
    Terapia, Romania
  • Isotretinoin Teva
    Teva, Denmark
  • Isotretinoína Aurovitas
    Aurovitas, Portugal
  • Isotretinoina Difa Cooper
    Difa Cooper, Italy
  • Isotretinoina Dutriec
    Dutriec, Paraguay
  • Isotretinoina EG
    EG, Italy
  • Isotretinoina Elifarma 20mg
    Elifarma, Paraguay
  • Isotretinoína EMS
    EMS, Brazil
  • Isotretinoína Gen.Germed
    Genéric.Germed, Brazil
  • Isotretinoína Generis
    Generis, Portugal
  • Isotretinoina Idifarma
    Ranbaxy, Spain
  • Isotretinoína Nova Quimica
    Nova Química Farmacêutica, Brazil
  • Isotretinoína Orotrex
    Medinfar, Portugal
  • Isotretinoina Pharma Arte
    Pharma Arte, Paraguay
  • Isotretinoína Pierre Fabre
    Pierre Fabre, Portugal
  • Isotretinoína Ranbaxy
    Ranbaxy, Brazil
  • Isotretinoina Servimedic
    Servimedic, Uruguay
  • Isotretinoina Stiefel
    Stiefel, Italy
  • Isotretinoina Sun
    SUN Pharmaceuticals Italia, Italy
  • Isotretinoína Valeant
    Valeant, Brazil
  • Isotretinoïne Aurobindo
    Aurobindo, Netherlands
  • Isotretinoine EG
    Eurogenerics, Belgium
  • Isotretinoïne Mylan
    Mylan, Netherlands
  • Isotretinoïne Sandoz
    Sandoz, Netherlands
  • Isotretinoïne SUN
    Sun Pharma, Netherlands
  • Isotretinoin-Humanity
    XL, Georgia
  • Isotretinoin-Mepha 10mg
    Mepha Pharma, Switzerland
  • Isotretinoin-Mepha 20mg
    Mepha Pharma, Switzerland
  • Isotretinoin-Mepha 40mg
    Mepha Pharma, Switzerland
  • Isotretinoin-PS
    Pfizer, Australia
  • Isotretinoin-ratiopharm
    ratiopharm, Germany
  • Isotretinoin-Teva 10 mg
    Teva, Hungary
  • Isotretinoin-Teva 20 mg
    Teva, Hungary
  • Isotrex
    GlaxoSmithKline, Germany; GlaxoSmithKline, Singapore; Stiefel, China; Stiefel, Germany; Stiefel, Spain; Stiefel, United Kingdom; Stiefel, Hong Kong; Stiefel, Ireland; Stiefel, Italy; Stiefel, Mexico; Stiefel, Philippines; Stiefel, Pakistan; Stiefel, Portugal; Stiefel, Taiwan; Stiefel, South Africa; Stiefel Laboratories Polska Sp. z.o.o., Poland; Unimed & Unihealth, Bangladesh
  • Isotrex 0.05%
    GlaxoSmithKline, Germany; Laboratorios Stiefel de Chile y Cia., Chile; Stiefel, Egypt
  • Isotrex 0.1%
    GlaxoSmithKline, Germany
  • Isotrex Eritromicina [+ Erythromycin]
    Stiefel, Spain
  • Isotrexin [+ Erythromycin]
    GlaxoSmithKline, Cyprus; GlaxoSmithKline, Germany; GlaxoSmithKline, Romania; GlaxoSmithKline, Singapore; GlaxoSmithKline, Turkey; Stiefel, Germany; Stiefel, United Kingdom; Stiefel, Italy; Stiefel, Lebanon; Stiefel, Portugal; Stiefel, Taiwan; Stiefel Laboratories Polska Sp. z.o.o., Poland
  • Isotroin
    Cipla, India; Cipla, Lebanon; Iasis Pharma, Greece; IASIS Pharmaceuticals Hellas, Cyprus; Servimedic, Uruguay
  • Izotek
    PharmaSwiss, Poland
  • Izotziaja
    Ziaja, Poland
  • Lisacne
    ABL, Ecuador; Laboratorios Andromaco, Chile
  • Lissage 10
    LIBRA, Uruguay
  • Lissage 20
    LIBRA, Uruguay
  • Locatret 0.1%
    GNP, Egypt
  • Mayesta
    Bama-Geve, Spain
  • Munderm [+ Erythromycin]
    Helba, Turkey; Merkez, Georgia
  • Myorisan
    VersaPharm, United States
  • Neotrex
    Serral, Mexico
  • Netlook
    Andalous, Egypt
  • Nimegen
    Medica Korea, South Korea; Medica Korea, Malaysia; Medica Korea, Singapore
  • Novacne
    Novofarm, Greece
  • Novacne 0.05%
    Novofarm, Greece
  • Oralne
    Laboratorio Deutsche Pharma, Chile
  • Oraret
    Palsons, India
  • Oratane
    Arrow Pharmaceuticals, Australia; Darier, Mexico; Douglas, Hong Kong; Douglas, New Zealand; Douglas, Singapore; Pharmaplan, South Africa
  • Piplex
    Mediderm, Chile; Mediderm, Peru
  • Procuta
    Expanscience, France
  • Reducar
    G.A. Pharmaceuticals, Hong Kong; Gap, Greece
  • Retin A 0.025%
    Sofeco, Egypt
  • Retin A 0.05%
    Janssen-Cilag, Egypt
  • Retmicin [+ Erythromycin]
    Verisfield, Greece
  • Roaccutan
    Investi, Argentina; Roche, Colombia; Roche, Ecuador; Roche, Italy; Roche, Peru; Roche, Paraguay; Roche, Venezuela; Roche Uruguay, Uruguay; Uhlmann-Eyraud Pharma, Switzerland
  • Roaccutan 10 mg
    Roche, Hungary
  • Roaccutan 10mg
    Roche Pharma Schweiz, Switzerland
  • Roaccutan 20 mg
    Roche, Hungary
  • Roaccutan 20mg
    Roche Pharma Schweiz, Switzerland
  • Roaccutane
    F. Hoffmann-La Roche, Macedonia; Hoffmann La Roche, Kuwait; Roche, Bosnia & Herzegowina; Roche, Bangladesh; Roche, Belgium; Roche, Bulgaria; Roche, Estonia; Roche, Egypt; Roche, Hong Kong; Roche, Croatia (Hrvatska); Roche, Ireland; Roche, Lithuania; Roche, Moldova; Roche, Philippines; Roche, Romania; Roche, Thailand; Roche, Turkey; Roche, Taiwan; Roche, South Africa; Roche Products, Australia; Roche Products, United Kingdom; Rp Scherer, Lebanon
  • Roaccutane 0.05%
    SERP, France
  • Roaccutane 10mg
    Roche, Israel; Roche, Luxembourg; Roche, Oman
  • Roaccutane 20mg
    Roche, Israel; Roche, Luxembourg; Roche, Oman
  • Roaccutane Roche
    Hoffmann-La Roche Ltd, Latvia
  • Roacnetan
    Productos Roche, Chile
  • Roacta
    MacroPhar, Thailand
  • Roacutan
    Roche, Brazil
  • Rocta
    Southern Cross Pharma, Australia
  • Rotaxin
    Hadjiconstantinou Bros, Cyprus
  • Rotren
    Sapiens Pharmaceuticals, Cyprus
  • Sotret
    Daiichi, Thailand; Elimera, Colombia; Terapia, Romania
  • Sotret 10mg
    Ranbaxy, Oman
  • Sotret 20 mg
    Ranbaxy, Oman; Terapia, Hungary
  • Stiefotrex
    GlaxoSmithKline A.B.E.E., Greece
  • Stiefotrex 0.05%
    GlaxoSmithKline A.B.E.E., Greece
  • Tai Er Si
    Sine Pharmaceutical, China
  • Teweisi
    Donghai Pharmaceutical, China
  • Tretin
    Target Pharma, Greece
  • Tretinac 10mg
    Recordati AG, Switzerland
  • Tretinac 20mg
    Recordati AG, Switzerland
  • Tretinac 5mg
    Recordati AG, Switzerland
  • Tretinex
    Abbott, Colombia; Medana Pharma, Poland
  • Tufacne
    AHPL, India
  • Xeractan 10mg
    Jazeera Pharmaceutical Industry JPI, Oman
  • Xeractan 20mg
    Jazeera Pharmaceutical Industry JPI, Oman
  • Zenatane
    Dr. Reddy's, United States
  • Zerocutan
    Joongwae Shinyak, South Korea
  • Zoretanin
    Actavis, Turkey

Glossary

TermDefinition
BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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