Benzocaine

In some countries, this medicine may only be approved for veterinary use.

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C05AD03,D04AB04,N01BA05,R02AD01

CAS registry number (Chemical Abstracts Service)

0000094-09-7

Chemical Formula

C9-H11-N-O2

Molecular Weight

165

Therapeutic Category

Anesthetic, local

Chemical Name

Etyl p-aminobenzoate (WHO)

Foreign Names

• Benzocainum (Latin)
• Benzocain (German)
• Benzocaïne (French)
• Benzocaína (Spanish)

Generic Names

• Benzocaina (OS: DCIT)
• Benzocaine (OS: BAN)
• Benzocaïne (OS: DCF)
• Ethyl Aminobenzoate (OS: JAN)
• 4-(Ethoxycarbonyl)aniline (IS)
• 4-14-00-01129 (IS: Beilstein)
• 4-Carbethoxyaniline (IS)
• Aethylium paraminobenzoicum (IS)
• Amben ethyl ester (IS)
• Anesthesine (IS)
• BRN 0638434 (IS)
• Éthoforme (IS)
• Euphagine (IS)
• Norcainum Anaesthesinum (IS: USSRP)
• Orthesine (IS)
• Parathesine (IS)
• Rhaetocaine (IS)
• Benzocain (PH: Ph. Eur. 8)
• Benzocaine (PH: BP 2016, Ph. Eur. 8, Ph. Int. 4, USP 38)
• Benzocaïne (PH: Ph. Eur. 8)
• Benzocainum (PH: Ph. Eur. 8, Ph. Int. 4)
• Ethyl Aminobenzoate (PH: JP XVI)

Brand Names

• AAA Sore Throat
  Manx, Malta; Manx Pharma, Cyprus
• AAA Spray (Benzocaine and Benzalkonium)
  Armour Pharmaceutical, Kenya
• akut-angin
  Divapharma, Slovakia
• Alipur (Benzocaine and Chlorhexidine)
  Omega Pharma, Portugal
• Americaine
  Insight, United States
• Amidalin (Benzocaine and Tyrothricin)
  Hexal, Brazil
• Amos Bioparsol-3 (Benzocaine and Thymol (veterinary use))
  Kommer, Netherlands
• Anaestherit 10%
  Dr. Ritsert Pharma, Austria
• Anaestherit 6%
  Dr. Ritsert Pharma, Austria
• Anaesthesin
  Ritsert, Germany
• Anbesol
  Paladin, Canada; Pfizer U.S., United States
• Anbesol Baby (pediatric)
  Paladin, Canada
• Anbesol Extra
  Paladin, Canada
• Anestefarin (Benzocaine and Chlorhexidine)
  Farline, Spain
• AnginHEXAL dolo
  Hexal, Germany
• Anginocom (Benzocaine and Chlorhexidine)
  Novag, Spain
• Aseptobron Caramelos (Benzocaine and Tyrothricin)
  Temis Lostalo, Argentina
• Auralgan (Benzocaine and Phenazone)
  Deston Therapeutics, United States; Paladin, Canada; Wyeth, Oman; Wyeth Consumer Healthcare, New Zealand
• Aurax (Benzocaine and Phenazone)
  Acella, United States
• Aurodex (Benzocaine and Phenazone)
  Major, United States
• Babee Teething (pediatric)
  SmithKline Beecham, United States
• Baby Gel (pediatric)
  Mediline, Israel
• Baby Kanka (pediatric)
  Sanfer, Mexico
• Baby Orajel
  Del Pharma, United States
• Babydent
  Stada, Lithuania
• Bagociletas (Benzocaine and Tyrothricin)
  Bagó, Argentina
• BBDent
  Maver, Chile; Maver, Peru
• Beezocain 20%
  Fukuchi Seiyaku, Japan
• Benzoak (veterinary use)
  ACD Pharmaceuticals AS, Norway
• Benzocaine 20%
  Sabaa, Egypt
• Benzocaine Hengrui
  Hengrui, China
• Benzodent
  Procter & Gamble, United States
• Benzokain
  Clinres, Slovenia
• Benzonac (Benzocaine and Diclofenac)
  Stedman, India
• Benz-O-Sthetic
  Geritrex, United States
• BiCOZENE
  Sandoz, United States
• Biomycetin (Benzocaine and Chloramphenicol)
  Juggat, India
• Bionet (Benzocaine and Cetalkonium)
  Church & Dwight, Canada
• Bisoral (Benzocaine and Cetylpyridinium)
  Intermed, Greece
• Boil-Ease
  Del Pharma, United States
• Boots Anaesthetic and Antibiotic (Benzocaine and Tyrothricin)
  The Boots Company, United Kingdom
• Bucodrin (Benzocaine and Chlorhexidine)
  Fardi, Spain
• Bucoseptol (Benzocaine and Dequalinium Chloride)
  Neo, Colombia
• Bucospray (Benzocaine and Chlorhexidine)
  Teofarma, Spain
• Bucoxol
  La Santé, Colombia
• Burneze
  Seton, Malta
• C.B. oint (Benzocaine and Chlorphenamine)
  CCPC, Taiwan
• Callicida Labsa (Benzocaine and Salicylic Acid)
  LABSA, Argentina
• Callivoro Marthand (Benzocaine and Salicylic Acid)
  Martinez Llenas, Spain
• Caramelos Antibioticos Fecofar (Benzocaine and Tyrothricin)
  Fecofar, Argentina
• Caramelos Antibioticos Richet (Benzocaine and Tyrothricin)
  Richet, Argentina
• Caramelos Multibióticos (Benzocaine and Dequalinium Chloride)
  Pharmavida, Peru
• Caramelos Oriental (Benzocaine and Hexylresorcinol)
  Oriental, Argentina
• Cartiflex (Benzocaine and Diethylamine Salicylate)
  ISA, Argentina
• Cepacaina (Benzocaine and Cetylpyridinium)
  Sanofi Aventis, Brazil; Sanofi-Aventis, Peru
• Cepacaine (Benzocaine and Cetylpyridinium)
  Bayer, New Zealand; Sanofi-Aventis, Mexico
• Cepacol Ultra Sore Throat Plus Cough (Benzocaine and Dextromethorphan)
  Combe, United States
• Cerax
  Millet-Franklin, Argentina
• Chigg Away (Benzocaine and Sulfur)
  Pierson Laboratory, United States
• Chloraseptic Total Score (Benzocaine and Dextromethorphan)
  Medtech, United States
• Chloromycetin (Benzocaine and Chloramphenicol)
  Pfizer, India
• Colluduo (Benzocaine and Chlorhexidine)
  Johnson & Johnson, Portugal
• Comtrex G Frambuesa
  Novartis Biosciences, Peru
• Cough X (Benzocaine and Dextromethorphan)
  B.F. Ascher, United States
• Dek (Benzocaine and Dequalinium)
  Materfarma, Portugal
• Dentigel
  Medifarma, Peru
• Dentispray
  Ferraz, Portugal; Viñas, Spain
• Dentocaine 7.5%
  Pharco, Egypt
• Dent-O-Kain
  Geritrex, United States
• Dentol
  Litfas, Lithuania
• Dentol-Baby (pediatric)
  Pharmascience, Lithuania
• Dentosedina (Benzocaine and Procaine)
  Teofarma, Italy
• Dequadin (Benzocaine and Benzocaine)
  Farmoquimica, Brazil
• Dequadin (Benzocaine and Dequalinium Chloride)
  Farmoquimica, Brazil
• Dermatran (Benzocaine and Thymol (veterinary use))
  A.A.-Vet, Netherlands
• Dermoplast
  Medtech, United States; Whitehall-Robins, United States
• Dermopur
  Prolab, Poland
• Detane
  Del, United States
• Dextro Toss Total (Benzocaine and Dextromethorphan)
  Medco, Peru
• Diadrop (Benzocaine and Chlorhexidine)
  Bial Portela, Portugal
• Dolo-Dobendan (Benzocaine and Cetylpyridinium)
  Reckitt Benckiser, Germany
• Dooz (Benzocaine and Tocopherol, α-)
  Reman, Egypt
• Earcalm (Benzocaine and Phenazone)
  Riyadh Pharma, Oman
• Ear-Gesic (Benzocaine and Phenazone, + Phenylephrine)
  Qualitest, United States
• Enemeez Plus (Benzocaine and Glycerol, + Docusate Sodium)
  Alliance, United States
• Enzymicine (Benzocaine and Neomycin)
  Ato Zizine, France
• Equate Vagicane (Benzocaine and Resorcinol)
  Calypark, Egypt
• Ethyl Aminobenzoate 10% Maruishi
  Maruishi Pharmaceutical, Japan
• Ethyl Aminobenzoate Maruishi
  Maruishi Pharmaceutical, Japan
• Ethyl Aminobenzoate Mylan
  Mylan Seiyaku, Japan
• Ethyl Aminobenzoate Yamazen Seiyaku
  Yamazen Seiyaku, Japan
• Fanaletas (Benzocaine and Tyrothricin)
  Lazar, Argentina
• Farindol (Benzocaine and Chlorhexidine)
  Ratiopharm, Spain
• Faringenilo (Benzocaine and Potassium Chloride)
  Diafarm, Spain
• Faringesic (Benzocaine and Chlorhexidine)
  Diafarm, Spain
• Filotricin A
  Ferring, Argentina
• Foille
  Blistex, United States
• Foille (Benzocaine and Benzyl Alcohol)
  Synthon Chile, Chile
• Fragiderm
  Mintlab Co., Chile
• Frenagar (Benzocaine and Chlorhexidine)
  McNeil, Spain
• Gargaril (Benzocaine and Chlorhexidine)
  Puerto Galiano, Spain
• Gargax (Benzocaine and Cetylpyridinium)
  Genomma Laboratories México, Mexico
• Gartricin
  Toll, Spain
• Garydol (Benzocaine and Chlorhexidine)
  Cinfa, Peru; Cinfa, Taiwan
• Gingicaine 20%
  Hakusui Trading, Japan
• Graneodin B
  Bristol-Myers Squibb, Ecuador
• Happy-Dent
  Gianfarma, Peru
• Hemoal (Benzocaine and Ephedrine)
  Reckitt Benckiser Healthcare, Spain
• Hemoal Forte (Benzocaine and Ephedrine)
  Reckitt Benckiser Healthcare, Spain
• Herposicc
  Pharmaselect, Austria
• Hexokain (Benzocaine and Chlorhexidine)
  Takeda Pharma, Denmark
• Hexoral (Benzocaine and Chlorhexidine)
  Johnson & Johnson, Russian Federation; McNeil, Czech Republic
• Hexoraletten (Benzocaine and Chlorhexidine)
  Goedecke, Bulgaria; McNeil, Lithuania
• Hexoraletten N (Benzocaine and Chlorhexidine)
  Johnson & Johnson, Latvia; McNeil, Romania
• Histacalm (Benzocaine and Zinc Oxide)
  ECU, Ecuador
• Hurricaine
  Beutlich, United States; Beutlich L.P. Pharmaceuticals, Israel; Clarben, Spain; Dental Technologies, Georgia; Vedefar, Belgium
• Hurricaine 20%
  AGSA Nippon, Japan
• Insecticum (Benzocaine and Diphenhydramin)
  Apomedica Pharmazeutische Produkte, Austria
• Ivy-Rid (Benzocaine and Benzethonium)
  Medique, United States
• Kalgaron (Benzocaine and Tyrothricin)
  Rafa, Israel
• Kalgaron Forte (Benzocaine and Tyrothricin)
  Rafa, Israel
• Kanka
  Blistex, Israel
• Kank-a
  Blistex, United States
• Kank-Eze (Benzocaine and Cetylpyridinium)
  Rider, Chile
• Kank-Eze Plus (Benzocaine and Cetylpyridium)
  Synthon Chile, Chile
• Lanacane
  Combe, United States; Reckitt & Colman, Spain
• Lanacane C (Benzocaine and Cetrimide)
  Wilson, New Zealand
• Li Di Nuo (Benzocaine and Zinc Oxide)
  BanZhou Pharmaceutical, China
• Lyndan NF (Benzocaine and Permethrin)
  Cassara, Argentina
• Major Oral Pain Relief
  Major, United States
• Medi-Keel (Benzocaine and Cetylpyridinium)
  Al Pharm, South Africa
• Mentocaína (Benzocaine and Tyrothricin)
  Azevedos, Portugal
• Merocaine (Benzocaine and Cetylpyridinium)
  SSL, Malta
• Miozets (Benzocaine and Tyrothricin)
  Uriach-Aquilea, Spain
• Mucopain
  ICPA, India
• Muelita Forte Gel
  Cabuchi, Argentina
• Muelita Gel Pediatrico (pediatric)
  Cabuchi, Argentina
• Myalgesic (Benzocaine and Salicylamide)
  Farmanic Chemipharma, Greece
• Nani Pre Dental
  Alter, Spain
• neo-angin Benzocain dolo
  Cassella-med, Germany
• Neocones (Benzocaine and Neomycin)
  Mab Dental, Spain; Septodont, Estonia; Septodont, Lithuania; Septodont, Latvia
• Néocones (Benzocaine and Neomycin)
  Septodont, France
• Neoseptolete Duo (Benzocaine and Cetylpyridinium)
  Krka, Czech Republic
• Neozalocaine (Benzocaine and Farmocaine)
  Neo Dental Chemical, Japan
• Nigepan (Benzocaine and Heparin)
  Nizhpharm, Russian Federation
• Noraver P Pastillas (Benzocaine and Cetylpyridinium)
  Tecnoquimicas, Colombia
• Noxacorn (Benzocaine and Acetylsalicylic Acid)
  Dexxon, Israel
• OlynHexo (Benzocaine and Chlorhexidine)
  Johnson & Johnson, Slovakia
• Orabase
  Colgate Oral Pharmaceuticals, United States
• Orabase-B
  Colgate Oral Pharmaceuticals, United States
• Orajel
  Church & Dwight UK, United Kingdom; Church And Dwight Canada, Lebanon; Del, United States
• Orajel Mouth-Aid
  Del Pharma, United States
• Orajel Pain Relief
  Del Pharma, United States
• OraMagic
  MPM Medical, United States
• Oramed
  Mirren, South Africa
• Orasol
  Goldline, United States
• Orimycetin Otic (Benzocaine and Chloramphenicol)
  Oriental, Taiwan
• Orochlor (Benzocaine and Chlorhexidine)
  Aspen Pharmacare Consumer, South Africa
• Orogel
  Square, Bangladesh
• Osmopak Plus (Benzocaine and Magnesium Sulfate)
  Teva Canada, Canada
• Otic Edge (Benzocaine and Policosanol, + Phenazone)
  River's Edge, United States
• Oticaina
  Bussié, Colombia; Bussié, Honduras
• Otocain (Benzocaine and Benzethonium, + Glycol)
  Jones Medical, United States
• Otocol (Benzocaine and Chloramphenicol)
  Amman Pharmaceutical, Lebanon
• Otosept (Benzocaine and Phenazone)
  Amriya, Egypt
• Otozin (Benzocaine and Glycerol, + Zinc Acetate, + Phenazone)
  Allegis Pharmaceuticals, United States
• Ou Ji
  Hengrui, China
• Pharynx (Benzocaine and Cetylpyridinium)
  DHA, Hong Kong; DHA, Malaysia
• Pinnacaine
  Sircle Laboratories, United States
• Prepacort H (Benzocaine and Hydrocortisone)
  Pfizer Italia, Italy
• Prones (Benzocaine and Cinchocaine)
  Nippon Shika Yakuhin Dental Pharm, Japan
• Puder plynny z anestezyna (Benzocaine and Zinc Oxide)
  Hasco-Lek, Poland
• Pulmosan (Benzocaine and Tyrothricin)
  Gezzi, Argentina
• Rafathricin + Benzocaine (Benzocaine and Tyrothricin)
  Rafa, Israel
• Relief Advance
  Bayer HealthCare, Russian Federation
• Rogadermis
  Lafedar, Argentina
• Salicrem (Benzocaine and Diethylamine)
  Gezzi, Argentina
• Sanilin (Benzocaine and Cetylpyridinium)
  Kley Hertz, Brazil
• Sarnacur (Benzocaine and Benzyl Benzoate)
  Markos, Peru
• Scaboma (Benzocaine and Lindane)
  Glenmark, India
• Sédorectal (veterinary use)
  Coophavet, France
• SensoGARD
  Block Drug, United States
• Septofort Forte Combi (Benzocaine and Chlorhexidine)
  Walmark, Slovakia
• Septol (Benzocaine and Chlorhexidine)
  Walmark, Bulgaria
• Septolete (Benzocaine and Cetylpyridinium)
  Krka, Malta; Krka, Portugal
• Septolete Plus (Benzocaine and Cetylpyridinium)
  Krka, Bosnia & Herzegowina; Krka, Bulgaria; Krka, Estonia; Krka, Georgia; Krka, Croatia (Hrvatska); Krka, Poland; Krka, Romania; Krka, Serbia; Krka, Slovakia; Krka Pharma, Russian Federation; Krka Tovarna Zdravil, Austria
• Sodrimax (Benzocaine and Hydroquinone, + Hydrocortisone)
  Pisa, Mexico
• Solarcaine
  Schering Plough, Brazil
• Soldrin (Benzocaine and Hydrocortisone, + Chloramphenicol)
  Pisa, Mexico
• Sting-Kill
  Randob, United States
• Tanac
  Del, United States
• Tantum Verde (Benzocaine and Benzydamine)
  Angelini, Portugal
• Terramycin (Benzocaine and Oxytetracycline (veterinary use))
  Zoetis, South Africa
• Tetra-Formula (Benzocaine and Dextromethorphan)
  Reese, United States
• Therevac-Plus (Benzocaine and Docusate Sodium, + Glycerol)
  Jones Medical, United States
• Tinarin (Benzocaine and Phenazone)
  Horizon, Egypt
• Toncils (Benzocaine and Chlorhexidine)
  Vitabalans, Estonia; Vitabalans, Lithuania
• Tonsilon (Benzocaine and Benzethonium, + Tyrothricin)
  Charoon Bhesaj, Thailand
• Topex 20%
  Pierre Fabre Médicament, France
• Topident Infantil (pediatric)
  Lamosan, Ecuador
• Topigel
  Clarben, Portugal
• Topispray
  Clarben, Spain
• TriOxin (Benzocaine and Chloroxylenol, + Hydrocortisone)
  Vertical Pharma, United States
• Tyricine (Benzocaine and Tyrothricin)
  Christo, Hong Kong
• Tyrothricin Co (Benzocaine and Tyrothricin, + Codeine)
  Jean-Marie Pharmacal, Hong Kong
• Tyrozets (Benzocaine and Thyrothricin)
  McNeil, Ireland; McNeil Products, United Kingdom
• Ultra Chloraseptic Anaesthetic
  Prestige Brands, Malta
• Ultracare
  Ultradent, Georgia
• Unguentine (Benzocaine and Resorcinol)
  Lee, United States
• Wasp-Eze (Benzocaine and Mepyramine)
  Seton, Malta
• Zilactin-B
  Zila, United States
• Zora C (Benzocaine and Benzalkonium)
  Cid, Egypt

Glossary

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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