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Benzocaine use while Breastfeeding

Medically reviewed by Last updated on Apr 2, 2022.

Drugs containing Benzocaine: Cepacol Sore Throat, Vagisil, Orajel, Dermoplast, Auralgan, Anbesol, Cetacaine, Retre-Gel, OraMagic Plus, Lanacane, Show all 150 »Medicone, Orajel Baby, Hurricaine, Chloraseptic Sore Throat Lozenges, Cepacol Extra Strength Sore Throat, Chloraseptic Max Sore Throat Lozenges, Topical Anesthetic Dental Gel, Trocaine, Chiggerex, Boil Ease Pain Relieving, Gumsol, Tanac, Pinnacaine, Benzotic, Benzodent, Cepacol Fizzlers, Spec-T, Anacaine, Maintain, Topex, Orabase, Play Longer, One Touch Advanced Gel, Exactacain, Trioxin, Dermoplast Pain Relieving, Vicks Formula 44 Custom Care Sore Throat Lozenges, Otic Edge, Treagan, PR Otic, Otic Care, OtiLam, Allergen, Auroto, A/B Otic, Otigesic, Rx-Otic, Aurodex, Aurogard, Dolotic, Aurax, Otogesic, Tympagesic, Chlorphenylcaine, Otozin, Neotic, Lanacane Anti-Itch, Dermoplast Antibacterial, Oticaine, Omedia, Americaine Otic, Otocain, Chloraseptic Sore Throat Relief Strips, Zilactin Tooth and Gum Instant Pain Reliever, Cepacol Sensations Warming, Cepacol Sore Throat & Coating, Cepacol Ultra, Sting Relief, Cepacol Dual Relief Sore Throat, Kank-a, Cepacol Sensations Hydra, BeeGentle, Opahl, Precaine B, Denti-Care Denti-Freeze, Benzo-Jel, Bicozene, Isodettes, Super Dent Topical Anesthetic Gel, Dent-O-Kain, Americaine, Laryngesic, Americaine Anesthetic Lubricant, Ora film, Topex Topical Anethetic, Numzident, Num-Zit, Detane, Foille Plus, Gelato Topical Anesthetic Gel, Mosco Nail A Cain, Outgro Pain Relief, Orabase with Benzocaine, Solarcaine First Aid Medicated Spray, Americaine Hemorrhoidal, Hem-Prep, Babee Teething Lotion, Rid-A-Pain, Chigger-Tox, Zilactin-B, Anbesol Cold Sore, Skeeter Stik, Anbesol Baby, Benz-O-Sthetic, Orajel Denture Plus, Caine Tips Oral Pain Relief, Orajel Overnight Cold Sore Patch, Adazin, Cepacol Anesthetic, Protac, Bucalsep Solution, Orajel Mouth-Aid Liquid, Orajel Mouth Sore Medicine Gel, Orasep Solution, Orasep Spray, Bucalsep Spray, Foille, MyOxin, Cepacol Extra Strength Sore Throat & Cough, Cough-X, Cepacol Dual Relief Sore Throat + Cough Spray, Cepacol Sore Throat + Cough Relief, Spec-T Sore Throat/Cough Suppressant, Cough-X Cough Relief, Chloraseptic Total Sore Throat+Cough Lozenges, Cepastat Sore Throat & Cough, Docusol Plus, Vacuant Plus, Therevac Plus, Enemeez Plus, Super T, Enznonuty, Cepacol Sensations Cooling, Chloraseptic Warming Sore Throat Lozenges, Sting-Kill, Cepacol Instamax, Cepacol Sore Throat with Pain Relief, VapoCOOL Sore Throat, Mucinex InstaSoothe Sore Throat + Pain Relief, Dendracin, Giltuss Bucalsep, Spec-T Sore Throat/Decongestant Lozenges, Dermagesic, Z-Xtra, Vagicaine, Vagisil Maximum Strength, Navogan, Triban, Tebamide Pediatric, Tebamide

Benzocaine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Topical benzocaine has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. Benzocaine should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia in children under 2 years of age.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider



US Food and Drug Administration. Risk of serious and potentially fatal blood disorder prompts FDA action on oral over-the-counter benzocaine products used for teething and mouth pain and prescription local anesthetics. 2018. https://www​​/drug-safety-and-availability​/risk-serious-and-potentially-fatal-blood-disorder-prompts-fda-action-oral-over-counter-benzocaine.

Substance Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Anesthetics, Local

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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