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Benzocaine use while Breastfeeding

Medically reviewed by Last updated on Jun 16, 2023.

Drugs containing Benzocaine: Cepacol Sore Throat, Orajel, Chloraseptic Sore Throat Lozenges, Dermoplast, Auralgan, Trocaine, Cetacaine, Otocain, Lanacane, Hurricaine, Show all 154 »Allergen, Benzodent, Orajel Baby (benzocaine formulation), Medicone, Benzotic, Zilactin-B, Enznonuty, Cepacol Extra Strength Sore Throat, Chloraseptic Max Sore Throat Lozenges, Cepacol Instamax, Aurax, Otogesic, Anbesol, Americaine, Anacaine, Ora film, Outgro Pain Relief, Babee Teething Lotion, Boil Ease Pain Relieving, One Touch Advanced Gel, Trioxin, Enemeez Plus, Mucinex InstaSoothe Sore Throat + Pain Relief, Dendracin, Giltuss Bucalsep, Vagisil, Otic Edge, Treagan, PR Otic, Otic Care, OtiLam, Auroto, A/B Otic, Otigesic, Rx-Otic, Aurodex, Aurogard, Dolotic, Tympagesic, Chlorphenylcaine, Otozin, Neotic, Tanac, Orajel Instant Pain Relief Severe, Lanacane Anti-Itch, Dermoplast Antibacterial, Oticaine, Omedia, Americaine Otic, Pinnacaine, Chloraseptic Sore Throat Relief Strips, Zilactin Tooth and Gum Instant Pain Reliever, Cepacol Sensations Warming, Cepacol Sore Throat & Coating, Cepacol Ultra, Sting Relief, Cepacol Fizzlers, Cepacol Dual Relief Sore Throat, Kank-a, Cepacol Sensations Hydra, BeeGentle, OraMagic Plus, Opahl, Precaine B, Denti-Care Denti-Freeze, Benzo-Jel, Bicozene, Isodettes, Spec-T, Super Dent Topical Anesthetic Gel, Topical Anesthetic Dental Gel, Dent-O-Kain, Anbesol Baby (benzocaine formulation), Laryngesic, Orabase Baby Teething Gel (benzocaine formulation), Americaine Anesthetic Lubricant, Chiggerex, Topex Topical Anethetic, Maintain, Numzident, Num-Zit, Detane, Foille Plus, Gelato Topical Anesthetic Gel, Mosco Nail A Cain, Orabase with Benzocaine, Solarcaine First Aid Medicated Spray, Americaine Hemorrhoidal, Hem-Prep, Rid-A-Pain, Chigger-Tox, Anbesol Cold Sore, Skeeter Stik, Retre-Gel, Topex, Orabase, Benz-O-Sthetic, Orajel Denture Plus, Play Longer, Caine Tips Oral Pain Relief, Orajel Overnight Cold Sore Patch, Exactacain, Adazin, Cepacol Anesthetic, Protac, Bucalsep Solution, Orajel Mouth-Aid Liquid, Orajel Mouth Sore Medicine Gel, Orasep Solution, Orasep Spray, Bucalsep Spray, Foille, MyOxin, Cepacol Extra Strength Sore Throat & Cough, Cough-X, Cepacol Dual Relief Sore Throat + Cough Spray, Cepacol Sore Throat + Cough Relief, Spec-T Sore Throat/Cough Suppressant, Cough-X Cough Relief, Chloraseptic Total Sore Throat+Cough Lozenges, Cepastat Sore Throat & Cough, Docusol Plus, Vacuant Plus, Therevac Plus, Super T, Cepacol Sensations Cooling, Chloraseptic Warming Sore Throat Lozenges, Sting-Kill, Dermoplast Pain Relieving, Vicks VapoCOOL Severe, Cepacol Sore Throat with Pain Relief, Vicks Formula 44 Custom Care Sore Throat Lozenges, Vicks VapoCOOL Sore Throat, VapoCOOL Sore Throat, Spec-T Sore Throat/Decongestant Lozenges, Dermagesic, Z-Xtra, Vagicaine, Vagisil Maximum Strength, Navogan, Triban, Tebamide Pediatric, Tebamide, Gumsol

Benzocaine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Topical benzocaine has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. Benzocaine should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia in children under 2 years of age.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider



US Food and Drug Administration. Risk of serious and potentially fatal blood disorder prompts FDA action on oral over-the-counter benzocaine products used for teething and mouth pain and prescription local anesthetics. 2018. https://www​​/drug-safety-and-availability​/risk-serious-and-potentially-fatal-blood-disorder-prompts-fda-action-oral-over-counter-benzocaine.

Substance Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Anesthetics, Local

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Further information

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