Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Diphtheria and Tetanus Toxoids Adsorbed (for Pediatric Use) (DT) (diphtheria toxoid/tetanus toxoid)
- interferon gamma-1b
Interactions between your drugs
tetanus toxoid interferon gamma-1b
Applies to: Diphtheria and Tetanus Toxoids Adsorbed (for Pediatric Use) (DT) (diphtheria toxoid/tetanus toxoid), interferon gamma-1b
GENERALLY AVOID: The concomitant administration of interferon gamma with vaccines may theoretically increase the risk of an exaggerated immune response. The exact mechanism is unknown, but believed to be related to interferon gamma's immunomodulatory effects.
MANAGEMENT: The manufacturer recommends avoiding concomitant use with vaccines.
References (3)
- (2021) "Product Information. Imukin (interferon gamma-1b)." Link Medical Products Pty Ltd T/A Link Pharmaceuticals, 4.0
- (2021) "Product Information. Actimmune (interferon gamma-1b)." Horizon Therapeutics USA Inc
- (2022) "Product Information. Immukin (interferon gamma-1b)." Clinigen Healthcare Ltd
interferon gamma-1b diphtheria toxoid
Applies to: interferon gamma-1b, Diphtheria and Tetanus Toxoids Adsorbed (for Pediatric Use) (DT) (diphtheria toxoid/tetanus toxoid)
GENERALLY AVOID: The concomitant administration of interferon gamma with vaccines may theoretically increase the risk of an exaggerated immune response. The exact mechanism is unknown, but believed to be related to interferon gamma's immunomodulatory effects.
MANAGEMENT: The manufacturer recommends avoiding concomitant use with vaccines.
References (3)
- (2021) "Product Information. Imukin (interferon gamma-1b)." Link Medical Products Pty Ltd T/A Link Pharmaceuticals, 4.0
- (2021) "Product Information. Actimmune (interferon gamma-1b)." Horizon Therapeutics USA Inc
- (2022) "Product Information. Immukin (interferon gamma-1b)." Clinigen Healthcare Ltd
Drug and food/lifestyle interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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