Drug Interaction Report

Consumer information for this interaction is not currently available.

ADJUST DOSING INTERVAL: The administration of inactivated, killed, or otherwise noninfectious vaccines during etrasimod therapy has not been studied but may be associated with a diminished or suboptimal immunologic response. Vaccination may be less effective if administered during and for up to 5 weeks after discontinuation of etrasimod therapy.

MANAGEMENT: According to some authorities, the immune response to vaccines may be reduced during and for at least 2 weeks after discontinuation of etrasimod therapy. In patients who have recently been vaccinated, etrasimod therapy should preferably be postponed for at least one month to allow the full effect of vaccination to occur.

Grapefruit juice may increase the blood levels of etrasimod. You should avoid grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with etrasimod unless directed otherwise by your doctor. Talk to your doctor if you have any questions or concerns. Contact your doctor if your condition changes or you experience increased side effects, such as fever, high temperature or flu-like symptoms, severe headache, confusion, seizures, dizziness, tiredness, lightheadedness, chest pain, shortness of breath, or irregular or abnormal heartbeat, blurriness or shadows in the center of your vision, and nausea, vomiting, abdominal pain, anorexia, or jaundice and/or dark urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.