Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- flortaucipir F 18
- methylene blue
Interactions between your drugs
methylene blue flortaucipir F-18
Applies to: methylene blue, flortaucipir F 18
Flortaucipir F-18 has been reported to bind with low nanomolar affinity to monoamine oxidase-A (MAO-A) and monoamine oxidase-B (MAO-B) in vitro. In vivo, flortaucipir F-18 has differential uptake in neocortical areas containing aggregated tau protein. Flortaucipir F-18 positron emission tomography (PET) signal was slightly reduced in vivo by rasagiline, a MAO-B inhibitor, in low tau, high MAO-B areas of the brain such as the nucleus accumbens, putamen, and caudate. However, according to the flortaucipir F-18 manufacturer, there is little potential for MAO binding to affect flortaucipir F-18 scan interpretation in neocortical areas. It is not known if other MAO inhibitors (MAOIs) or agents with MAOI activity may interact.
References (1)
- (2022) "Product Information. Tauvid (flortaucipir F-18)." Lilly, Eli and Company
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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