Drug Interaction Report

Using delavirdine together with rifabutin is not recommended. Combining these medications can significantly decrease the blood levels of delavirdine, which may reduce its effectiveness in treating HIV infection. In addition, delavirdine may increase the blood levels of rifabutin, which could increase the risk of side effects such as low white blood cell counts, joint pain, skin discoloration, and inflammation of the eye. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using delavirdine together with omeprazole is not recommended. By reducing stomach acid, omeprazole can decrease the absorption and blood levels of delavirdine and make the medication less effective against HIV. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with delavirdine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.