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Drug Interaction Report

1 potential interaction and/or warning found for the following 2 drugs:

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Interactions between your drugs

Moderate

reteplase conestat alfa

Applies to: reteplase, conestat alfa

GENERALLY AVOID: C1 esterase inhibitors inhibit proteases in the coagulation/fibrinolytic system and may inhibit tissue plasminogen activators (tPAs). Complexation of C1 esterase inhibitor and tPA has been observed in scientific studies. However, the interaction has not been studied during clinical use of these agents concomitantly.

MANAGEMENT: Simultaneous administration of a C1 esterase inhibitor and a tPA should preferably be avoided.

References (1)
  1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Drug and food interactions

No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No duplication warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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