Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- amphotericin b cholesteryl sulfate
- Raplon (rapacuronium)
Interactions between your drugs
amphotericin B cholesteryl sulfate rapacuronium
Applies to: amphotericin b cholesteryl sulfate, Raplon (rapacuronium)
MONITOR: Amphotericin commonly causes renal potassium and magnesium wasting. As a result, serum potassium is decreased, and the pharmacologic effects of some neuromuscular blocking agents are enhanced.
MANAGEMENT: To decrease or prevent this interaction, magnesium and potassium levels should be monitored, and the patient's body stores of potassium and magnesium should be replenished even before the expected fall in serum potassium occurs.
References (4)
- Miller R, Bates J (1969) "Amphotericin B toxicity." Ann Intern Med, 71, p. 1089-95
- Cushard WG, Kohanim M, Lantis LR (1969) "Blastomycosis of bone." J Bone Joint Surg Am, 51A, p. 704-12
- "Product Information. Abelcet (amphotericin B lipid complex)." Liposome Company Inc, The
- (2022) "Product Information. Amphotec (amphotericin B cholesteryl sulfate)." Sequus Pharmaceuticals Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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