Drug Interaction Report

The following interaction applies only if you are taking potassium in a solid formulation (i.E., tablet or capsule swallowed whole) for potassium supplementation:

Talk to your doctor before using potassium oral tablets or capsules together with trospium. Depending on the dose of trospium and your overall physical health, combining these medications may increase the irritant effects of potassium on your stomach and upper intestine. This can rarely result in ulcers, bleeding, and other gastrointestinal injury. Contact your doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools during treatment with these medications. Alternatively, a liquid formulation of potassium may be considered when used in combination with trospium. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Trospium should be taken on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. You may experience reduced absorption of trospium in the presence of food. This will make it easier for your body to absorb the medication.