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Drug Interaction Report

2 potential interactions and/or warnings found for the following 2 drugs:

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Interactions between your drugs

Major

levobunolol ophthalmic formoterol

Applies to: Betagan (levobunolol ophthalmic), Bevespi Aerosphere (formoterol / glycopyrrolate)

Using levobunolol ophthalmic together with formoterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, levobunolol ophthalmic can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks. Levobunolol ophthalmic is normally not recommended if you have asthma, a history of asthma, or severe chronic obstructive pulmonary disease (COPD). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact or are less likely to interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

glycopyrrolate food

Applies to: Bevespi Aerosphere (formoterol / glycopyrrolate)

Ask your doctor before using glycopyrrolate together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No duplication warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.