Drug Interaction Report
8 potential interactions and/or warnings found for the following 2 drugs:
- Nordette-28 (ethinyl estradiol / levonorgestrel)
- Urelief Plus (butabarbital / hyoscyamine / phenazopyridine)
Interactions between your drugs
ethinyl estradiol butabarbital
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel), Urelief Plus (butabarbital / hyoscyamine / phenazopyridine)
Butabarbital may decrease the effectiveness of ethinyl estradiol. If you are using low-dose contraceptives, there is an increased risk of breakthrough bleeding and unintended pregnancy during combined therapy with butabarbital. Alternative or additional methods of birth control should be used while taking butabarbital. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones. You may notice symptoms of increased hot flashes, vaginal dryness or menstrual abnormalities. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
levonorgestrel butabarbital
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel), Urelief Plus (butabarbital / hyoscyamine / phenazopyridine)
Butabarbital may decrease the effectiveness of levonorgestrel. If you are using low-dose contraceptives, there is an increased risk of breakthrough bleeding and unintended pregnancy during combined therapy with butabarbital. Alternative or additional methods of birth control should be used while taking butabarbital. If you take hormone replacement for menopause, notify your doctor if you have decreased efficacy of your hormones. You may notice symptoms of increased hot flashes, vaginal dryness or menstrual abnormalities. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
Drug and food interactions
butabarbital food
Applies to: Urelief Plus (butabarbital / hyoscyamine / phenazopyridine)
Ask your doctor before using butabarbital together with ethanol, this can add to dizziness, drowsiness and other side effects of butabarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with butabarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
levonorgestrel food
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel)
Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with levonorgestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
hyoscyamine food
Applies to: Urelief Plus (butabarbital / hyoscyamine / phenazopyridine)
Ask your doctor before using hyoscyamine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel)
Information for this minor interaction is available on the professional version.
levonorgestrel food
Applies to: Nordette-28 (ethinyl estradiol / levonorgestrel)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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