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Tromethamine

Excipient (pharmacologically inactive substance)

What is it?

As an inactive ingredient, tromethamine (C4H11NO3) is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. Tromethamine as a pharmaceutical agent is used to treat metabolic acidosis (an electrolyte imbalance). Metabolic acidosis can have many causes. It often occurs after heart bypass surgery or cardiac arrest.[1][2]

[1] Drugs.com. Tromethamine. Accessed February 14, 2015 at http://www.drugs.com/mtm/tromethamine.html

[2] PubChem. Tromethamine. Accessed February 14, 2105 at http://pubchem.ncbi.nlm.nih.gov/compound/tromethamine

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