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Excipient (pharmacologically inactive substance)

Medically reviewed by Last updated on July 16, 2020.

What is it?

As an inactive ingredient, tromethamine (C4H11NO3) is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. Tromethamine as a pharmaceutical agent is used to treat metabolic acidosis (an electrolyte imbalance). Metabolic acidosis can have many causes. It often occurs after heart bypass surgery or cardiac arrest.[1][2]

Top Medications with this excipient


[1] Tromethamine. Accessed February 14, 2015 at

[2] PubChem. Tromethamine. Accessed February 14, 2105 at

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.